SCHEMBL2189980

SCHEMBL2189980

C=CC(=O)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.38
ALDH1A1 P00352 3/20 0.36
CYP2C19 P33261 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
AKT1 P31749 1/20 0.36
TGM2 P21980 2/20 0.33
THRA P10827 1/20 0.33
RIPK1 Q13546 1/20 0.33
MAPT P10636 2/20 0.33
TSHR P16473 2/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KMT2A Q03164 1/20 0.31
GSTO1 P78417 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5973451 0.86 HCAR2 (0.37) ALDH1A1MAPTTSHRHSD17B10TDP1
SCHEMBL5973442 0.86 HCAR2 (0.37) ALDH1A1MAPTTSHRHSD17B10TDP1
SCHEMBL5974325 0.86 HCAR2 (0.37) ALDH1A1MAPTTSHRHSD17B10TDP1
SCHEMBL4647510 0.85 MAPT (0.37) ALDH1A1CYP2C19MAPTTSHRHSD17B10
SCHEMBL476117 0.82 CES2 (0.38) ALDH1A1CYP2C19CYP3A4MAPTTSHR
SCHEMBL28219395 0.82 HCAR2 (0.44) MAPTHSD17B10
SCHEMBL28326061 0.82 ELANE (0.32)
SCHEMBL9411666 0.81 THRB (0.41) THRBALDH1A1CYP2C19CYP3A4CYP2C9
SCHEMBL476116 0.81 TDP1 (0.34) ALDH1A1CYP2C19MAPTTSHRHSD17B10
SCHEMBL4643573 0.81 MAPT (0.34) CYP2C19MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111534186-B Fluorescent visual fluorine-silicon electronic protective coating and preparation method thereof 浙江大学 2021-04-23 CN claimed
CN-111534186-A Fluorescent visual fluorine-silicon electronic protective coating and preparation method thereof 浙江大学 2020-08-14 CN claimed
EP-1539861-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF Sigmakalon Services B.V. (NL) 2005-06-15 EP claimed
WO-2004007591-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF SIGMAKALON SERVICES B.V. (NL) 2004-01-22 WO claimed
CN-111868184-B Copolymer for antifouling paint composition and antifouling paint composition comprising the same 日东化成株式会社 2023-08-18 CN disclosed
CN-115135677-A Compound and polymer composition containing the same 三菱化学株式会社 2022-09-30 CN disclosed
CN-111187548-B Fluorosilicone composite photocatalytic antibacterial antifouling paint and preparation method thereof 浙江大学衢州研究院 2021-11-30 CN disclosed
CN-111187530-B Fluorine-silicon composite visible light catalytic antibacterial antifouling paint and preparation method thereof 浙江大学衢州研究院 2021-11-26 CN disclosed
CN-111534186-B Fluorescent visual fluorine-silicon electronic protective coating and preparation method thereof 浙江大学 2021-04-23 CN disclosed
CN-110198998-B Copolymer for antifouling paint composition, and antifouling paint composition 日东化成株式会社 2021-04-13 CN disclosed
CN-111868184-A Copolymer for antifouling paint composition, and antifouling paint composition containing same 日东化成株式会社 2020-10-30 CN disclosed
CN-111534186-A Fluorescent visual fluorine-silicon electronic protective coating and preparation method thereof 浙江大学 2020-08-14 CN disclosed
EP-1277816-B1 ANTIFOULING COATING MATERIAL, ANTIFOULING COATING FILM, SUBMERGED STRUCTURE, AND ANTIFOULING METHOD BASF COATINGS JAPAN LTD (JP) 2006-11-08 EP disclosed
EP-1479737-B1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC (US) 2006-08-16 EP disclosed
EP-1479737-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions Atofina Chemicals, Inc. (US) 2004-11-24 EP disclosed
US-20040138332-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2004-07-15 US disclosed
US-20030225184-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2003-12-04 US disclosed
EP-1367100-A1 Triarylsilyl (meth) acryloyl-containing polymers for marine coating compositions ATOFINA CHEMICALS, INC. (US) 2003-12-03 EP disclosed
US-20030158292-A1 Antifouling coating material, antifouling coating film, submerged structure, and antifouling method NITTO KASEI CO., LTD. (JP) 2003-08-21 US disclosed
EP-1277816-A1 ANTIFOULING COATING MATERIAL, ANTIFOULING COATING FILM, SUBMERGED STRUCTURE, AND ANTIFOULING METHOD BASF NOF Coatings Co., Ltd., (JP) 2003-01-22 EP disclosed