Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 13/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4711922 | 0.94 | BDKRB1 (0.60) | BDKRB1ACHEGSK3BF10 | |
| SCHEMBL4717773 | 0.91 | BDKRB1 (0.56) | BDKRB1ACHEGSK3BF10 | |
| SCHEMBL4716382 | 0.90 | BDKRB1 (0.67) | BDKRB1ACHEGSK3B | |
| SCHEMBL4712113 | 0.89 | BDKRB1 (0.59) | BDKRB1ACHEGSK3BF10 | |
| SCHEMBL4713599 | 0.88 | ACHE (0.59) | BDKRB1ACHEGSK3BF10 | |
| SCHEMBL4713232 | 0.88 | BDKRB1 (0.53) | BDKRB1KCNK3KCNK9 | |
| SCHEMBL4713296 | 0.88 | BDKRB1 (0.68) | BDKRB1F10 | |
| SCHEMBL4713548 | 0.87 | BDKRB1 (0.72) | BDKRB1F10 | |
| SCHEMBL4714750 | 0.85 | BDKRB1 (0.66) | BDKRB1F10 | |
| SCHEMBL4716016 | 0.85 | BDKRB1 (0.66) | BDKRB1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877401-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | Elan Pharmaceuticals Inc. (US) | 2008-01-16 | — | — | EP | claimed |
| WO-2006113140-A2 | NOVEL COMPOUNDS USEFUL FOR BRADYKININ B1 RECEPTOR ANTAGONISM | ELAN PHARMACEUTICALS, INC. (US) | 2006-10-26 | — | — | WO | claimed |
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | ELAN PHARMACEUTICALS, INC. | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | BDKRB1, BDKRB2, NPBWR1 | BDKRB1 1/4885ALDH1A1 3073/4885ACHE 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.