Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 13/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3406838 | 0.88 | KDM4E (0.43) | KDM4EPKMOXER1GPR84 | |
| SCHEMBL3170365 | 0.83 | MEN1 (0.39) | KDM4EPKMKMT2A | |
| SCHEMBL9454685 | 0.72 | ALDH1A1 (0.55) | KDM4EKMT2A | |
| SCHEMBL9455142 | 0.72 | ALDH1A1 (0.43) | KDM4EPKMKMT2A | |
| SCHEMBL15570393 | 0.69 | HCAR2 (0.40) | KDM4E | |
| SCHEMBL9264403 | 0.68 | KDM4E (0.47) | KDM4EPKMGPR84 | |
| SCHEMBL12989131 | 0.68 | KDM4E (0.47) | KDM4EPKMGPR84 | |
| SCHEMBL12989313 | 0.68 | KDM4E (0.47) | KDM4EPKMGPR84 | |
| SCHEMBL4717877 | 0.68 | SMN1; SMN2 (0.31) | KMT2A | |
| SCHEMBL23147412 | 0.68 | ALDH1A1 (0.40) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996588-A1 | NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE ATI AND ETA RECEPTORS | Torrent Pharmaceuticals Ltd (IN) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007100295-A1 | NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE ATI AND ETA RECEPTORS | TORRENT PHARMACEUTICALS LTD (IN) | 2007-09-07 | — | — | WO | disclosed |