Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765268 | 0.96 | TSHR (0.40) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL4768992 | 0.92 | NPC1 (0.40) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL4765058 | 0.92 | RAB9A (0.37) | TSHRTP53ALDH1A1LMNARAB9A | |
| SCHEMBL4762535 | 0.90 | TSHR (0.40) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL4766959 | 0.89 | ALDH1A1 (0.41) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL4769632 | 0.89 | ALDH1A1 (0.41) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL4762455 | 0.89 | NPC1 (0.40) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL4767737 | 0.85 | RAB9A (0.34) | TSHRTP53CYP3A4ALDH1A1LMNA | |
| SCHEMBL4765428 | 0.83 | TSHR (0.38) | TSHRTP53ALDH1A1LMNARAB9A | |
| SCHEMBL4765479 | 0.81 | LMNA (0.36) | TSHRTP53CYP3A4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439169-B1 | DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-7273878-B2 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-25 | — | — | US | disclosed |
| US-20040248872-A1 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1439169-A1 | DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248872-A1 | Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor | DDT, WEE1, NOTUM | TSHR 2772/4885TP53 1193/4885CYP3A4 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.