SCHEMBL4763198

SCHEMBL4763198

c1ccc(CN(Cc2ccccc2)Sc2nc3ccccc3s2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
HPGD P15428 3/20 0.54
HSD17B10 Q99714 3/20 0.54
FBP1 P09467 2/20 0.54
ADRA2A P08913 1/20 0.54
ADORA3 P0DMS8 1/20 0.54
DRD2 P14416 1/20 0.54
ALOX15 P16050 1/20 0.54
ADRA2B P18089 1/20 0.54
ADRA2C P18825 1/20 0.54
DRD1 P21728 1/20 0.54
MC5R P33032 1/20 0.54
OPRM1 P35372 1/20 0.54
DRD3 P35462 1/20 0.54
OPRK1 P41145 1/20 0.54
CCR2 P41597 1/20 0.54
HTR6 P50406 1/20 0.54
SLC6A3 Q01959 1/20 0.54
PDK1 Q15118 1/20 0.54
TDP1 Q9NUW8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29483756 1.00 ALDH1A1 (0.54) ALDH1A1HPGDHSD17B10FBP1ADRA2A
SCHEMBL29483757 1.00 ALDH1A1 (0.54) ALDH1A1HPGDHSD17B10FBP1ADRA2A
SCHEMBL4427712 0.85 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10FBP1ADRA2A
SCHEMBL11589539 0.85 POLB (0.57) ALDH1A1HPGDHSD17B10FBP1ADRA2A
SCHEMBL29494838 0.81 FBP1 (0.59) ALDH1A1HPGDHSD17B10FBP1ADRA2A
SCHEMBL80423 0.81 FBP1 (0.59) ALDH1A1HPGDHSD17B10FBP1ADRA2A
SCHEMBL11749605 0.80 FBP1 (0.56) ALDH1A1HPGDHSD17B10FBP1ADRA2A
SCHEMBL1193419 0.78 FBP1 (0.56) ALDH1A1HPGDHSD17B10FBP1ADRA2A
SCHEMBL29494839 0.78 FBP1 (0.56) ALDH1A1HPGDHSD17B10FBP1ADRA2A
SCHEMBL712848 0.77 ALDH1A1 (0.53) ALDH1A1HPGDHSD17B10FBP1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718700-B2 Rubber-steel cord composite and pneumatic tire TOYO TIRE CORPORATION (JP) 2023-08-08 US disclosed
US-11718699-B2 Rubber-steel cord composite and pneumatic tire using the same TOYO TIRE CORPORATION (JP) 2023-08-08 US disclosed
US-11718699-B2 Rubber-steel cord composite and pneumatic tire using the same TOYO TIRE CORPORATION (JP) 2023-08-08 US disclosed
US-11718700-B2 Rubber-steel cord composite and pneumatic tire TOYO TIRE CORPORATION (JP) 2023-08-08 US disclosed
EP-3959201-A1 METHOD FOR PRODUCING N,N-DISUBSTITUTED BENZTHIAZOLYL-SULFENAMIDES LANXESS Deutschland GmbH (DE) 2022-03-02 EP disclosed
US-20210388185-A1 PNEUMATIC TIRE TOYO TIRE CORPORATION (JP) 2021-12-16 US disclosed
US-20210388198-A1 RUBBER-STEEL CORD COMPOSITE AND PNEUMATIC TIRE USING THE SAME TOYO TIRE CORPORATION (JP) 2021-12-16 US disclosed
US-20210388144-A1 RUBBER-STEEL CORD COMPOSITE AND PNEUMATIC TIRE TOYO TIRE CORPORATION (JP) 2021-12-16 US disclosed
US-20210388143-A1 RUBBER-STEEL CORD COMPOSITE AND PNEUMATIC TIRE USING THE SAME TOYO TIRE CORPORATION (JP) 2021-12-16 US disclosed
WO-2020216780-A1 METHOD FOR PRODUCING N,N-DISUBSTITUTED BENZTHIAZOLYL-SULFENAMIDES LANXESS DEUTSCHLAND GMBH (DE) 2020-10-29 WO disclosed
EP-3730485-A1 METHOD FOR THE PREPARATION OF N,N DISUBSTITUTED BENZTHIAZOLYL-SULFENAMIDES LANXESS Deutschland GmbH (DE) 2020-10-28 EP disclosed
JP-2008308632-A RUBBER COMPOSITION, AND COMPOSITE MATERIAL COMPRISING METAL MATERIAL AND THE RUBBER COMPOSITION OOUCHI SHINKO KAGAKU KOGYO KK 2008-12-25 JP disclosed
US-6929769-B2 Nitrile rubber mixtures with a low tendency towards mold contamination BAYER AKTIENGESELLSCHAFT (DE) 2005-08-16 US disclosed
US-6765064-B2 Mixtures of olefin polymers and nitrile rubbers BAYER AKTIENGESELLSCHAFT (DE) 2004-07-20 US disclosed
US-20040014892-A1 Mixtures of olefin polymers and nitrile rubbers LANXESS DEUTSCHLAND GMBH (DE) 2004-01-22 US disclosed
US-20030181604-A1 Nitrile rubber mixtures with a low tendency towards mold contamination ARLANXEO DEUTSCHLAND GMBH (DE) 2003-09-25 US disclosed
EP-1331074-A1 Nitrile rubber compositions with reduced tendency to mould fouling Bayer Aktiengesellschaft (DE) 2003-07-30 EP disclosed
US-6573333-B2 Wherein there is no phase segregation; moldings characterized by improved mechanical properties and better resistance in mineral oils; profiles, belts, rings, seals, damping elements, coatings, coverings BAYER AKTIENGESELLSCHAFT (DE) 2003-06-03 US disclosed
US-20020077424-A1 Mixtures of olefin polymers and nitrile rubbers LANXESS DEUTSCHLAND GMBH (DE) 2002-06-20 US disclosed
EP-0721946-A1 Process for preparing N,N-dialkyl-, -dicycloalkyl-, -diaryl or-diaralkyl-benzthiazolyl-sulfenamides BAYER AG (DE) 1996-07-17 EP disclosed