SCHEMBL80423

SCHEMBL80423

CCN(CC)Sc1nc2ccccc2s1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.59
ALDH1A1 P00352 6/20 0.58
HSD17B10 Q99714 4/20 0.58
HPGD P15428 3/20 0.58
ADRA2A P08913 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
DRD2 P14416 1/20 0.58
ALOX15 P16050 1/20 0.58
ADRA2B P18089 1/20 0.58
ADRA2C P18825 1/20 0.58
DRD1 P21728 1/20 0.58
MC5R P33032 1/20 0.58
OPRM1 P35372 1/20 0.58
DRD3 P35462 1/20 0.58
OPRK1 P41145 1/20 0.58
CCR2 P41597 1/20 0.58
HTR6 P50406 1/20 0.58
SLC6A3 Q01959 1/20 0.58
PDK1 Q15118 1/20 0.58
TDP1 Q9NUW8 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29494838 1.00 FBP1 (0.59) FBP1ALDH1A1HSD17B10HPGDADRA2A
SCHEMBL29494839 0.87 FBP1 (0.56) FBP1ALDH1A1HSD17B10HPGDADRA2A
SCHEMBL1193419 0.87 FBP1 (0.56) FBP1ALDH1A1HSD17B10HPGDADRA2A
SCHEMBL1193644 0.86 FBP1 (0.49) FBP1ALDH1A1HSD17B10HPGDADRA2A
SCHEMBL15158154 0.86 ALDH1A1 (0.49) FBP1ALDH1A1HSD17B10HPGDADRA2A
SCHEMBL13827005 0.85 FBP1 (0.58) FBP1ALDH1A1HSD17B10HPGDADRA2A
SCHEMBL29494842 0.84 FBP1 (0.54) FBP1ALDH1A1HSD17B10HPGDADRA2A
SCHEMBL10475867 0.84 FBP1 (0.54) FBP1ALDH1A1HSD17B10HPGDADRA2A
SCHEMBL11748720 0.84 FBP1 (0.65) FBP1ALDH1A1HSD17B10HPGDADRA2A
SCHEMBL15463366 0.83 FBP1 (0.52) FBP1ALDH1A1HSD17B10HPGDADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10889686-B2 Benzothiazoles as latent catalysts for benzoxazine resins HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2021-01-12 US claimed
WO-2020133736-A1 HYDROPHOBIC STEEL WIRE RUBBER-COATED CORD AND PREPARATION METHOD THEREOF 怡维怡橡胶研究院有限公司 2020-07-02 WO claimed
US-20190225752-A1 Benzothiazoles as Latent Catalysts for Benzoxazine Resins HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2019-07-25 US claimed
CN-109762214-A A kind of hydrophobicity steel wire covers glue cord and preparation method thereof 怡维怡橡胶研究院有限公司 2019-05-17 CN claimed
EP-3455287-A1 BENZOTHIAZOLES AS LATENT CATALYSTS FOR BENZOXAZINE RESINS Huntsman Advanced Materials Americas LLC (US) 2019-03-20 EP claimed
CN-106084334-B A kind of superelevation strength Natural rubber sheet and preparation method thereof 南京东润特种橡塑有限公司 2018-09-11 CN claimed
WO-2017196805-A1 BENZOTHIAZOLES AS LATENT CATALYSTS FOR BENZOXAZINE RESINS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2017-11-16 WO claimed
CN-106700527-A Flame-retardant polyamide resin composition and preparation method thereof 湖州利鹏新材料科技有限公司 2017-05-24 CN claimed
US-8562927-B2 Absorbent solution containing a breakdown inhibitor derived from thiazole or from oxazole and absorption process for acid compounds contained in a gaseous effluent IFP (FR) 2013-10-22 US claimed
US-20120308452-A1 ABSORBENT SOLUTION CONTAINING A BREAKDOWN INHIBITOR DERIVED FROM THIAZOLE OR FROM OXAZOLE AND ABSORPTION PROCESS FOR ACID COMPOUNDS CONTAINED IN A GASEOUS EFFLUENT IFP (FR) 2012-12-06 US claimed
EP-0677546-B1 Rubber/polyester cord composite and tire with component thereof GOODYEAR TIRE & RUBBER (US) 1999-07-14 EP claimed
US-5663358-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-02 US claimed
EP-0785206-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-07-23 EP claimed
EP-0775726-A1 Curable ethylene-alpha olefin-diene elastomer composition UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-05-28 EP claimed
EP-0677546-A1 Rubber/polyester cord composite and tire with component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 1995-10-18 EP claimed
EP-0154437-A2 Substituted dithiocarbamylurea accelerators UNIROYAL CHEMICAL COMPANY, Inc. (US) 1985-09-11 EP claimed
US-4430466-A Benzothiazyl sulfenamides as scorch retardants for mercaptosilane-coupled silica filled-rubber compounds PHILLIPS PETROLEUM COMPANY (US) 1984-02-07 US claimed
US-4229325-A VULCANIZABLE COPOLYMERS OR TERPOLYMERS, A SULFUR DONOR, A DELAYED ACTION ACCELERATOR; GEL-FREE EXXON RESEARCH & ENGINEERING CO. (US) 1980-10-21 US claimed
US-4215022-A GEL-FREE EXXON RESEARCH & ENGINEERING CO. (US) 1980-07-29 US claimed
US-4153584-A High molecular weight high unsaturation C4 -C10 isoolefin conjugated diolefin copolymers and multipolymers containing methylcyclopentadiene EXXON RESEARCH & ENGINEERING CO. (US) 1979-05-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10889686-B2 Benzothiazoles as latent catalysts for benzoxazine resins LOX, KDM4A, PGLS FBP1 1392/4885ALDH1A1 707/4885HSD17B10 3109/4885
US-20190225752-A1 Benzothiazoles as Latent Catalysts for Benzoxazine Resins KDM4A, LOX, KDM5A FBP1 1568/4885ALDH1A1 583/4885HSD17B10 3433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.