SCHEMBL4763371

SCHEMBL4763371

CC(CCCCOC(=O)c1ccc(Cl)nc1)=C(F)F

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.54
LMNA P02545 1/20 0.54
POLB P06746 3/20 0.49
RAB9A P51151 3/20 0.49
MAPT P10636 2/20 0.49
PKM P14618 1/20 0.49
GAA P10253 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.46
CHRNB2 P17787 1/20 0.44
CHRNA7 P36544 1/20 0.44
CHRNA4 P43681 1/20 0.44
TDP1 Q9NUW8 3/20 0.43
NPC1 O15118 2/20 0.42
DGAT1 O75907 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4762177 0.85 MAPT (0.43) L3MBTL1LMNARAB9AMAPTGAA
SCHEMBL4770755 0.83 MAPT (0.50) L3MBTL1LMNARAB9AMAPTSMN1; SMN2
SCHEMBL4763360 0.82 L3MBTL1 (0.47) L3MBTL1LMNARAB9AMAPTSMN1; SMN2
SCHEMBL14560618 0.80 L3MBTL1 (0.63) L3MBTL1LMNAPOLBRAB9AMAPT
SCHEMBL4767504 0.79 LMNA (0.66) L3MBTL1LMNAPOLBMAPTGAA
SCHEMBL4767579 0.79 L3MBTL1 (0.52) L3MBTL1LMNAPOLBRAB9AMAPT
SCHEMBL4767355 0.79 NAPRT (0.42) L3MBTL1LMNAPOLBRAB9AMAPT
SCHEMBL4769270 0.78 TDP1 (0.46) L3MBTL1LMNARAB9AMAPTSMN1; SMN2
SCHEMBL4769605 0.77 CHRNB2 (0.48) SMN1; SMN2CHRNB2CHRNA7CHRNA4TDP1
SCHEMBL9455931 0.77 TSHR (0.55) L3MBTL1LMNARAB9AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1439169-B1 DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR KUMIAI CHEMICAL INDUSTRY CO (JP) 2008-08-06 EP disclosed
US-7273878-B2 Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-09-25 US disclosed
US-20040248872-A1 Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2004-12-09 US disclosed
EP-1439169-A1 DIFLUOROALKENE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE SAME, AND INTERMEDIATE THEREFOR KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2004-07-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040248872-A1 Difluoroalkene derivative, pest control agent containing the same, and intermediate therefor DDT, WEE1, NOTUM L3MBTL1 17/4885LMNA 4259/4885POLB 3681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.