Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339710 | 0.89 | DPP4 (0.41) | EPHX2PTGER1SLC2A2GSK3AGSK3B | |
| SCHEMBL338896 | 0.88 | ALDH1A1 (0.40) | EPHX2PTGER1SLC2A2GSK3AGSK3B | |
| SCHEMBL339320 | 0.74 | DPP4 (0.41) | EPHX2PTGER1SLC2A2GSK3AGSK3B | |
| SCHEMBL4724684 | 0.73 | DPP4 (0.36) | EPHX2DPP4 | |
| SCHEMBL340129 | 0.72 | ALDH1A1 (0.39) | SLC2A2DPP4DPP8DPP9P2RX7 | |
| SCHEMBL338817 | 0.70 | DPP4 (0.52) | EPHX2DPP4DPP8DPP9 | |
| SCHEMBL338734 | 0.70 | SLC2A2 (0.46) | EPHX2SLC2A2DPP4DPP8DPP9 | |
| SCHEMBL339781 | 0.69 | ALDH1A1 (0.38) | DPP4DPP8DPP9 | |
| SCHEMBL4767528 | 0.69 | CNR1 (0.40) | EPHX2P2RX7 | |
| SCHEMBL338930 | 0.68 | CRHR1 (0.41) | SLC2A2DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004643-A1 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007113226-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2007-10-11 | — | — | WO | disclosed |