SCHEMBL4763776

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4774233	0.90	MALT1 (0.38)	MALT1KMOALDH1A1KMT2ARXFP1
	SCHEMBL4772896	0.85	SYK (0.40)	SYKALDH1A1KMT2AMEN1
	SCHEMBL4768384	0.85	PDE5A (0.42)	SYKRXFP1PDE5AKCNH2
	Hydrochloric Acid SCHEMBL4772337	0.85	SYK (0.39)	SYKALDH1A1KMT2AMEN1
	SCHEMBL4769957	0.84	SYK (0.35)	SYKHTTKMT2ARXFP1MEN1
	SCHEMBL4772893	0.83	HDAC3 (0.41)	ALDH1A1HTTKMT2AMEN1
	SCHEMBL4768601	0.83	KMT2A (0.42)	KMOTRPV3ALDH1A1HTTKMT2A
	Hydrochloric Acid SCHEMBL4770496	0.82	HDAC3 (0.40)	ALDH1A1HTTKMT2AMEN1
	Hydrochloric Acid SCHEMBL4774118	0.82	KMT2A (0.44)	KMOTRPV3ALDH1A1HTTKMT2A
	SCHEMBL4768652	0.82	MAPK1 (0.40)	SYKALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.