Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1204842 | 0.80 | TSHR (0.35) | TSHR | |
| SCHEMBL28097907 | 0.77 | PGD (0.36) | PGDTSHR | |
| SCHEMBL28114414 | 0.76 | ADH1B (0.33) | — | |
| SCHEMBL5622191 | 0.76 | ADH1B (0.30) | — | |
| SCHEMBL11081449 | 0.75 | ADH1B (0.32) | — | |
| SCHEMBL6292489 | 0.72 | ADH1B (0.30) | — | |
| SCHEMBL23510216 | 0.71 | PPARA (0.43) | — | |
| SCHEMBL7808944 | 0.70 | MAPT (0.42) | TSHR | |
| SCHEMBL11378416 | 0.69 | PGD (0.32) | PGD | |
| SCHEMBL7767539 | 0.69 | ADH1B (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572678-A4 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARM INC (US) | 2008-05-07 | — | — | EP | disclosed |
| EP-1572678-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | Elan Pharmaceuticals, Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056319-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS INC. (US) | 2004-07-08 | — | — | WO | disclosed |
| WO-2002062340-A1 | HIGHLY LIPOPHILIC CAMPTOTHECIN PRODRUGS, METHODS OF PREPARATION, AND FORMULATIONS THEREOF | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2002-08-15 | — | — | WO | disclosed |