Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932576 | 0.79 | PTGS2 (0.38) | MAPTKMT2ATSHRMEN1TAAR1 | |
| SCHEMBL7819088 | 0.78 | KMT2A (0.41) | KMT2ATSHRMEN1TAAR1TACR1 | |
| SCHEMBL5792443 | 0.74 | TACR1 (0.35) | MAPTKMT2ATSHRMEN1TAAR1 | |
| SCHEMBL5788687 | 0.74 | TACR1 (0.35) | MAPTKMT2ATSHRMEN1TAAR1 | |
| SCHEMBL31037765 | 0.71 | MAPT (0.47) | MAPTKMT2AGABBR2GABBR1ATM | |
| SCHEMBL4800772 | 0.70 | EEF2K (0.47) | MAPTKMT2AGABBR2GABBR1MEN1 | |
| SCHEMBL4764470 | 0.70 | PGD (0.35) | TSHR | |
| SCHEMBL3439003 | 0.69 | SRC (0.37) | CTSSCTSKCYP2C19 | |
| SCHEMBL14625499 | 0.69 | KMT2A (0.58) | KMT2ATSHRMEN1TACR1CYP2C19 | |
| SCHEMBL206552 | 0.69 | KMT2A (0.49) | KMT2ATSHRMEN1TAAR1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1078919-A1 | SYNTHESIS OF $g(a)-AMINO-$g(a)',$g(a)'-DIHALOKETONES AND PROCESS FOR THE PREPARATION OF $g(b)-AMINO ACID DERIVATIVES BY THE USE OF THE SAME | KANEKA CORPORATION (JP) | 2001-02-28 | — | — | EP | disclosed |