SCHEMBL4764633

SCHEMBL4764633

[O-][n+]1ccccc1-c1[c]nccn1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1379942 0.74 LMNA (0.34) LMNAHTT
SCHEMBL29727517 0.70 LMNA (0.52) LMNAHTT
SCHEMBL871319 0.70 LMNA (0.52) LMNAHTT
SCHEMBL10921966 0.68 MEN1 (0.33)
SCHEMBL559143 0.67 MTOR (0.39)
SCHEMBL30305663 0.67 KDM4E (0.50) LMNAHTT
SCHEMBL1367753 0.67 KDM4E (0.50) LMNAHTT
SCHEMBL28762856 0.67 METAP2 (0.38) LMNAHTT
SCHEMBL27684655 0.66 LMNA (0.48) LMNAHTT
SCHEMBL4635144 0.65 LMNA (0.43) LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009002-A1 New process for the manufacture of 1H-imidazo [4,5-c]-quinoline ring systems INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2008-12-31 EP disclosed