Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3193347 | 0.82 | CA2 (0.49) | CA1PTPN1CA2MEN1ALDH1A1 | |
| SCHEMBL3193462 | 0.78 | SERPINE1 (0.53) | CA1CA2MEN1ALDH1A1KMT2A | |
| SCHEMBL3204698 | 0.76 | NR1I2 (0.53) | CA1CA12CA9CA2MEN1 | |
| SCHEMBL3185435 | 0.74 | SERPINE1 (0.52) | CA1CA2MEN1ALDH1A1KMT2A | |
| SCHEMBL3202333 | 0.71 | PPARG (0.49) | PPARGNTSR1ACE | |
| SCHEMBL3202345 | 0.71 | PPARG (0.49) | PPARGNTSR1ACE | |
| SCHEMBL3186142 | 0.70 | FPR2 (0.53) | — | |
| SCHEMBL27718316 | 0.70 | FPR2 (0.53) | — | |
| SCHEMBL3195456 | 0.68 | TRPM8 (0.51) | MEN1ALDH1A1KMT2A | |
| SCHEMBL3197128 | 0.68 | PPARG (0.53) | CA2PPARGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919866-A2 | SUBSTITUTED INDOLES AND USE THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-05-14 | — | — | EP | claimed |
| WO-2007022321-A2 | SUBSTITUTED INDOLES AND USE THEREOF | WYETH (US) | 2007-02-22 | — | — | WO | claimed |