⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846845 | 0.75 | — | — | |
| SCHEMBL6056744 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL6056737 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL318619 | 0.71 | — | — | |
| SCHEMBL607413 | 0.71 | — | — | |
| SCHEMBL23535032 | 0.71 | DGAT1 (0.32) | — | |
| SCHEMBL11336060 | 0.71 | — | — | |
| SCHEMBL9656486 | 0.71 | GAA (0.42) | — | |
| SCHEMBL1547727 | 0.69 | — | — | |
| SCHEMBL1698329 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102365101-A | Tissue adhesives and sealants comprising polyglycerol aldehydes | DU PONT | 2012-02-29 | — | — | CN | disclosed |
| CN-102361911-A | Polyglycerol aldehydes | DU PONT | 2012-02-22 | — | — | CN | disclosed |
| EP-2411062-A1 | TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE | Actamax Surgical Materials LLC (US) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010111594-A1 | TISSUE ADHESIVE AND SEALANT COMPRISING POLYGLYCEROL ALDEHYDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-30 | — | — | WO | disclosed |