Known targets — ChEMBL curated mechanism
TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8
The experimentally established mechanism targets of Vinorelbine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A known ✓ | P04350 | 7/20 | 1.00 |
| ▸ | TUBB known ✓ | P07437 | 7/20 | 1.00 |
| ▸ | TUBA3C known ✓ | P0DPH7 | 7/20 | 1.00 |
| ▸ | TUBA1B known ✓ | P68363 | 7/20 | 1.00 |
| ▸ | TUBA4A known ✓ | P68366 | 7/20 | 1.00 |
| ▸ | TUBB4B known ✓ | P68371 | 7/20 | 1.00 |
| ▸ | TUBB3 known ✓ | Q13509 | 7/20 | 1.00 |
| ▸ | TUBB2A known ✓ | Q13885 | 7/20 | 1.00 |
| ▸ | TUBB8 known ✓ | Q3ZCM7 | 7/20 | 1.00 |
| ▸ | TUBA3E known ✓ | Q6PEY2 | 7/20 | 1.00 |
| ▸ | TUBA1A known ✓ | Q71U36 | 7/20 | 1.00 |
| ▸ | TUBA1C known ✓ | Q9BQE3 | 7/20 | 1.00 |
| ▸ | TUBB6 known ✓ | Q9BUF5 | 7/20 | 1.00 |
| ▸ | TUBB2B known ✓ | Q9BVA1 | 7/20 | 1.00 |
| ▸ | TUBB1 known ✓ | Q9H4B7 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 5/20 | 1.00 |
| ▸ | TACR2 | P21452 | 1/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vinorelbine SCHEMBL12277732 | 1.00 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Vinorelbine SCHEMBL16786345 | 1.00 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Vinorelbine SCHEMBL13575786 | 1.00 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Vinorelbine SCHEMBL13524297 | 1.00 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Vinorelbine SCHEMBL10018526 | 1.00 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Vinorelbine SCHEMBL23077835 | 1.00 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Vinorelbine SCHEMBL1653160 | 1.00 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Vinorelbine SCHEMBL18220724 | 1.00 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Vinorelbine SCHEMBL21610430 | 1.00 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Vinorelbine SCHEMBL15113116 | 1.00 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 154763 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144890-A1 | ANTIBODY DRUG CONJUGATE COMPRISING NMT INHIBITOR CONJUGATED TO AN ANTIBODY | MyricX Pharma Limited (GB) | 2026-05-28 | — | — | US | claimed |
| EP-4748859-A2 | CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF | The Regents of the University of California (US) | 2026-05-27 | — | — | EP | claimed |
| EP-4747263-A1 | LIPID NANOPARTICLES AND USES THEREOF | University of Connecticut (US) | 2026-05-27 | — | — | EP | claimed |
| CN-122075497-A | Use of NLRP3 agonist for tumor treatment | — | 2026-05-26 | — | — | CN | claimed |
| US-12637498-B2 | PDLIM2 as a biomarker for cancer and as an anti-cancer treatment target | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2026-05-26 | — | — | US | claimed |
| CN-116209439-B | Cereblon protein modulators | Saint Jude Children's Research Hospital Ltd. (US) | 2026-05-26 | — | — | CN | claimed |
| US-20260137700-A1 | PHARMACEUTICAL COMBINATION OF PRMT5 INHIBITOR AND DNA DAMAGE-INDUCING SUBSTANCE | SK BIOPHARMACEUTICALS CO LTD (KR) | 2026-05-21 | — | — | US | claimed |
| US-20260137686-A1 | SOLID PHARMACEUTICAL FORMULATION OF PARP INHIBITORS AND USE THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2026-05-21 | — | — | US | claimed |
| US-20260141533-A1 | QUANTITATIVE IMAGING BIOMARKER FOR LUNG CANCER | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2026-05-21 | — | — | US | claimed |
| WO-2026105121-A1 | ANTICANCER FORMULATIONS AND USES THEREOF | INTRAGEL THERAPEUTICS LTD. (IL) | 2026-05-21 | — | — | WO | claimed |
| WO-1997040835-A1 | TREATMENT OF CARCINOMAS USING SQUALAMINE IN COMBINATION WITH OTHER ANTI-CANCER AGENTS | MAGAININ PHARMACEUTICALS INC. (US) | 1997-11-06 | — | — | WO | claimed |
| EP-0804173-A1 | CONTROLLED RELEASE BIODEGRADABLE MICROSPHERES AND METHOD OF PREPARATION | PIERRE FABRE MEDICAMENT (FR) | 1997-11-05 | — | — | EP | claimed |
| US-5620985-A | ANTICANCER AGENTS | PIERRE FABRE MEDICAMENT (FR) | 1997-04-15 | — | — | US | claimed |
| EP-0709090-A2 | Compositions for treating resistant tumors | ELI LILLY AND COMPANY (US) | 1996-05-01 | — | — | EP | claimed |
| WO-1996011677-A1 | METHODS FOR TREATING RESISTANT TUMORS | ELI LILLY AND COMPANY (US) | 1996-04-25 | — | — | WO | claimed |
| WO-1995028149-A1 | CONTROLLED RELEASE BIODEGRADABLE MICROSPHERES AND METHOD OF PREPARATION | PIERRE FABRE MEDICAMENT (FR) | 1995-10-26 | — | — | WO | claimed |
| EP-0393575-B1 | Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent | SEARLE & CO (US) | 1994-03-16 | — | — | EP | claimed |
| EP-0393575-A1 | Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent | G.D. Searle & Co. (US) | 1990-10-24 | — | — | EP | claimed |
| EP-0317401-A1 | Pharmaceutical composition for parenteral administration of navelbine | PIERRE FABRE MEDICAMENT (FR) | 1989-05-24 | — | — | EP | claimed |
| US-4307100-A | Nor bis-indole compounds usable as medicaments | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1981-12-22 | — | — | US | claimed |