SCHEMBL4765283

SCHEMBL4765283

Nc1ccc(N)c(C(F)(F)F)c1I

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.35
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6313808 0.81 KIF11 (0.36) NOTUMKIF11
SCHEMBL29620304 0.81 KIF11 (0.36) NOTUMKIF11
SCHEMBL24118139 0.77 KDM4E (0.37) NOTUM
SCHEMBL22990621 0.74 KIF11 (0.32) KIF11
SCHEMBL13385875 0.72 TSHR (0.39) NOTUMKIF11
SCHEMBL29579355 0.71 CYP3A4 (0.38)
SCHEMBL8543050 0.71 CYP3A4 (0.38)
SCHEMBL5794355 0.70 TSHR (0.43)
SCHEMBL10749956 0.70 IMPDH2 (0.32) KIF11
SCHEMBL438930 0.70 MPL (0.38) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2001676-A1 CAPACITIVE POLYIMIDE LAMINATE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-17 EP claimed
EP-2001942-A1 PROCESS FOR PREPARING POLYIMIDE BASED COMPOSITIONS USEFUL IN HIGH FREQUENCY CIRCUITRY APPLICATIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-17 EP claimed
WO-2007126533-A1 CAPACITIVE POLYIMIDE LAMINATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-08 WO claimed
WO-2007117372-A1 PROCESS FOR PREPARING POLYIMIDE BASED COMPOSITIONS USEFUL IN HIGH FREQUENCY CIRCUITRY APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-10-18 WO claimed