SCHEMBL476546

SCHEMBL476546

C=Cc1ccc(C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.33
HDAC8 Q9BY41 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21066247 0.94 ALDH1A1 (0.46) ALDH1A1TSHRTDP1HDAC8NR1H2
SCHEMBL8383958 0.92 ALDH1A1 (0.44) ALDH1A1TSHRTDP1HDAC8NR1H2
SCHEMBL7667697 0.88 ALDH1A1 (0.41) ALDH1A1TSHRCYP1A2
SCHEMBL476554 0.86 ALDH1A1 (0.52) ALDH1A1TSHRTDP1HDAC8NR1H2
SCHEMBL16626146 0.86 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8NR1H2
SCHEMBL16626135 0.80 ALDH1A1 (0.50) ALDH1A1TSHRHDAC8CYP1A2
SCHEMBL1134055 0.79 ALDH1A1 (0.44) ALDH1A1TSHRTDP1HDAC8NR1H2
SCHEMBL18242328 0.78 CYP1A2 (0.31) CYP1A2
SCHEMBL16626142 0.78 ALDH1A1 (0.54) ALDH1A1TSHRTDP1HDAC8
SCHEMBL10453844 0.77 ALDH1A1 (0.52) ALDH1A1TSHRTDP1HDAC8NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2200646-A None JP disclosed
CN-110621711-A Photocurable composition containing fluorine-based polymer 捷恩智株式会社 2019-12-27 CN disclosed
EP-2103636-B1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION JNC CORP (JP) 2016-07-20 EP disclosed
US-8445613-B2 Polymer and surface-treating agent containing the polymer JNC CORPORATION (JP) 2013-05-21 US disclosed
US-8293442-B2 Resin particle, toner, and image forming method and process cartridge using the same RICOH COMPANY, LTD. (JP) 2012-10-23 US disclosed
EP-2096128-B1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION JNC CORP (JP) 2012-02-01 EP disclosed
US-7989560-B2 Fluorine-containing polymer and resin composition CHISSO CORPORATION (JP) 2011-08-02 US disclosed
US-7868112-B2 Fluorine-containing polymer and resin composition CHISSO CORPORATION (JP) 2011-01-11 US disclosed
US-20100137540-A1 Polymer and Surface-Treating Agent Containing the Polymer CHISSO CORPORATION (JP) 2010-06-03 US disclosed
US-20100093951-A1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION JNC CORPORATION (JP) 2010-04-15 US disclosed
US-20100075245-A1 RESIN PARTICLE, TONER, AND IMAGE FORMING METHOD AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2010-03-25 US disclosed
US-20100063222-A1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION CHISSO CORPORATION (JP) 2010-03-11 US disclosed
EP-2130845-A1 POLYMER AND SURFACE-TREATING AGENT CONTAINING THE POLYMER Chisso Corporation (JP) 2009-12-09 EP disclosed
EP-2103636-A1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION Chisso Corporation (JP) 2009-09-23 EP disclosed
EP-2096128-A1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION Chisso Corporation (JP) 2009-09-02 EP disclosed
EP-0729041-B1 Water-Absorptive soft contact lens MENICON CO LTD (JP) 2001-11-28 EP disclosed
US-5741830-A COPOLYMER OF A FLUORINE CONTAINING STYRENE DERIVATIVE AND N,N-DIMETHYL(METH)ACRYLAMIDE MENICON CO., LTD. (JP) 1998-04-21 US disclosed
EP-0729041-A2 Water-Absorptive soft contact lens Menicon Co., Ltd. (JP) 1996-08-28 EP disclosed
JP-H02200646-A FLUOROALKYL GROUP-CONTAINING AROMATIC DERIVATIVE AND PREPARATION THEREOF NIPPON OIL & FATS CO LTD 1990-08-08 JP disclosed