SCHEMBL1134055

SCHEMBL1134055

C=Cc1ccc(C(F)(F)C(O)(F)C(F)(F)F)cc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.39
NR1H2 P55055 6/20 0.37
NR1H3 Q13133 6/20 0.37
TDP1 Q9NUW8 1/20 0.35
CYP1A2 P05177 1/20 0.32
PTGS1 P23219 1/20 0.32
AR P10275 1/20 0.31
NQO2 P16083 1/20 0.31
HDAC8 Q9BY41 1/20 0.30
PGK1 P00558 1/20 0.30
PGK2 P07205 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476554 0.83 ALDH1A1 (0.52) ALDH1A1TSHRNR1H2NR1H3TDP1
SCHEMBL16626146 0.83 ALDH1A1 (0.58) ALDH1A1TSHRNR1H2NR1H3TDP1
SCHEMBL1284428 0.82 PGK1 (0.40) ALDH1A1TSHRNR1H2NR1H3PGK1
SCHEMBL643498 0.79 NR1H2 (0.56) ALDH1A1NR1H2NR1H3
SCHEMBL476546 0.79 ALDH1A1 (0.48) ALDH1A1TSHRNR1H2NR1H3TDP1
SCHEMBL16626142 0.79 ALDH1A1 (0.54) ALDH1A1TSHRTDP1HDAC8CA1
SCHEMBL5662892 0.78 TP53 (0.40) ALDH1A1TSHRTDP1PGK1PGK2
SCHEMBL21066247 0.78 ALDH1A1 (0.46) ALDH1A1TSHRNR1H2NR1H3TDP1
Styrene SCHEMBL4917329 0.77 ALDH1A1 (0.64) ALDH1A1TSHRNR1H2NR1H3TDP1
SCHEMBL16626135 0.77 ALDH1A1 (0.50) ALDH1A1TSHRCYP1A2PTGS1NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113122227-A Composite material, preparation method thereof, light-emitting film and display device TCL集团股份有限公司 2021-07-16 CN claimed
JP-1293337-A None JP disclosed
JP-2120355-A None JP disclosed
JP-2120354-A None JP disclosed
JP-2120356-A None JP disclosed
CN-113348188-B Phenolic hydroxyl group-containing resin, photosensitive composition, resist film, curable composition, and cured product DIC株式会社 2024-05-10 CN disclosed
CN-117590691-A Photosensitive resin composition 中央硝子株式会社 2024-02-23 CN disclosed
CN-117321109-A Phenolic hydroxyl group-containing resin DIC株式会社 2023-12-29 CN disclosed
CN-116209690-A Phenolic hydroxyl group-containing resin, resin composition for alkali-developable resist, resist-curable resin composition, and method for producing phenolic hydroxyl group-containing resin DIC株式会社 2023-06-02 CN disclosed
CN-115873214-A Epoxy resin, photosensitive resin composition, resist film, curable composition, and cured film DIC株式会社 2023-03-31 CN disclosed
US-7951525-B2 Low outgassing photoresist compositions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-05-31 US disclosed
EP-2285845-A1 LOW OUTGASSING PHOTORESIST COMPOSITIONS International Business Machines Corporation (US) 2011-02-23 EP disclosed
US-20100062368-A1 LOW OUTGASSING PHOTORESIST COMPOSITIONS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-03-11 US disclosed
WO-2010025983-A1 LOW OUTGASSING PHOTORESIST COMPOSITIONS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-03-11 WO disclosed
US-6943271-B2 Process for producing fluorine-containing, polymerizable styrene monomer and intermediates used in same CENTRAL GLASS COMPANY, LIMITED (JP) 2005-09-13 US disclosed
US-20040002612-A1 Process for producing fluorine-containing, polymerizable styrene monomer and intermediates used in same CENTRAL GLASS COMPANY, LIMITED (JP) 2004-01-01 US disclosed
JP-H02120354-A RESIN COMPOSITION FOR OPTICAL MATERIAL TOSOH CORP 1990-05-08 JP disclosed
JP-H02120355-A RESIN COMPOSITION FOR OPTICAL MATERIAL TOSOH CORP 1990-05-08 JP disclosed
JP-H02120356-A RESIN COMPOSITION FOR OPTICAL MATERIAL TOSOH CORP 1990-05-08 JP disclosed
JP-H01293337-A NEGATIVE TYPE PHOTORESIST COMPOSITION TOSOH CORP 1989-11-27 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040002612-A1 Process for producing fluorine-containing, polymerizable styrene monomer and intermediates used in same PFAS, AFF1, AFF2 ALDH1A1 1392/4885TSHR 2096/4885NR1H2 4260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.