Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4765255 | 0.96 | SLC2A1 (0.43) | HRH3RAB9ANPC1TP53GAA | |
| SCHEMBL4768623 | 0.80 | RAB9A (0.58) | HRH3RAB9ANPC1TP53GAA | |
| SCHEMBL4771087 | 0.80 | AURKA (0.58) | TP53SMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL4767717 | 0.79 | MEN1 (0.58) | HRH3RAB9ANPC1TP53GAA | |
| SCHEMBL4768161 | 0.79 | POLB (0.56) | HRH3RAB9ANPC1TP53GAA | |
| SCHEMBL4767370 | 0.78 | MEN1 (0.58) | HRH3RAB9ANPC1TP53GAA | |
| SCHEMBL4772665 | 0.78 | HRH3 (0.52) | HRH3RAB9ANPC1TP53GAA | |
| SCHEMBL5823896 | 0.78 | HRH3 (0.54) | HRH3RAB9ANPC1TP53HTT | |
| Trifluoroacetic Acid SCHEMBL4765400 | 0.77 | AURKA (0.52) | RAB9ATP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4777120 | 0.77 | NPY5R (0.54) | HRH3RAB9ANPC1TP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |