SCHEMBL476633

SCHEMBL476633

C=Cc1ccccc1C(F)C=C

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.32
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4893011 0.83 LMNA (0.46) ALDH1A1TSHR
SCHEMBL8521683 0.82 ALDH1A1 (0.44) ALDH1A1TSHRNFE2L2
SCHEMBL28713554 0.82 ALDH1A1 (0.38) ALDH1A1
SCHEMBL6271995 0.79 HPGD (0.42) ALDH1A1TSHR
SCHEMBL526123 0.76 ALDH1A1 (0.48) ALDH1A1TSHR
SCHEMBL9749392 0.76
SCHEMBL4853721 0.76
SCHEMBL5141462 0.76 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL2944385 0.75 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL1076557 0.74 ALDH1A1 (0.41) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265499-B1 POLYMERIZING MIXTURE MENICON CO., LTD. (JP) 2001-07-24 US claimed
US-5741830-A COPOLYMER OF A FLUORINE CONTAINING STYRENE DERIVATIVE AND N,N-DIMETHYL(METH)ACRYLAMIDE MENICON CO., LTD. (JP) 1998-04-21 US claimed
JP-8311082-A None JP disclosed
CN-113906062-A Polymers and nanoparticles for displacement 沙特阿拉伯石油公司 2022-01-07 CN disclosed
EP-2103636-B1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION JNC CORP (JP) 2016-07-20 EP disclosed
US-9086628-B2 Resist protective film-forming composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-07-21 US disclosed
US-8933251-B2 Fluorinated monomer of cyclic acetal structure, polymer, resist protective coating composition, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-01-13 US disclosed
US-20130231491-A1 FLUORINATED MONOMER OF CYCLIC ACETAL STRUCTURE, POLYMER, RESIST PROTECTIVE COATING COMPOSITION, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-09-05 US disclosed
US-8445613-B2 Polymer and surface-treating agent containing the polymer JNC CORPORATION (JP) 2013-05-21 US disclosed
US-8431323-B2 Fluorinated monomer of cyclic acetal structure, polymer, resist protective coating composition, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-30 US disclosed
US-20130084517-A1 RESIST PROTECTIVE FILM-FORMING COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-04 US disclosed
EP-0577112-B1 Polyfluorohydrocarbon group containing monomers, their polymers and applications of the polymers ASAHI GLASS CO LTD (JP) 1997-05-21 EP disclosed
JP-H08311082-A POLYFLUOROARALKYLSILANE DERIVATIVE AND ITS PRODUCTION NEOS CO LTD 1996-11-26 JP disclosed
US-5565607-A ADDS FLEXIBILITY TO STYRENE-TYPE MONOMERS; IMPROVES WATER AND OIL REPELLENCY AND ADHESIVE PROPERTIES ASAHI GLASS COMPANY LTD. (JP) 1996-10-15 US disclosed
US-5556929-A FROM UNSATURATED DIESTER WITH URETHANE AND FLUORINE GROUPS AND ACRYLATED SILOXANE, CONTACT LENSES MENICON CO., LTD. (JP) 1996-09-17 US disclosed
EP-0729041-A2 Water-Absorptive soft contact lens Menicon Co., Ltd. (JP) 1996-08-28 EP disclosed
EP-0577112-A2 Polyfluorohydrocarbon group containing monomers, their polymers and applications of the polymers ASAHI GLASS COMPANY LTD. (JP) 1994-01-05 EP disclosed
EP-0318604-B1 SOFT OCULAR LENS AND METHOD FOR ITS PREPARATION Tomei Sangyo Kabushiki Kaisha (JP) 1993-03-10 EP disclosed
US-4904421-A SOFT POLYMER LENS IMPREGNATED WITH A MONOMER WHICH IS THEN POLYMERIZED TO FORM A HARD POLYMER BLEND; MACHINING; REMOVAL OF HARD POLYMER. TOMEI SANGYO KABUSHIKI KAISHA (JP) 1990-02-27 US disclosed
EP-0318604-A1 Soft ocular lens and method for its preparation Tomei Sangyo Kabushiki Kaisha (JP) 1989-06-07 EP disclosed