Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL596057 | 1.00 | LMNA (0.59) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| Sulfuric Acid SCHEMBL28088103 | 0.97 | LMNA (0.56) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL28966026 | 0.97 | LMNA (0.56) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL28966023 | 0.97 | LMNA (0.56) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL28966024 | 0.97 | LMNA (0.56) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL28229405 | 0.97 | LMNA (0.56) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL28966025 | 0.97 | LMNA (0.56) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL996850 | 0.91 | TSHR (0.65) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL718256 | 0.91 | TSHR (0.65) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL301148 | 0.89 | TSHR (0.62) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2410857-A1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | Merck Sharp & Dohme Corp. (US) | 2012-02-01 | — | — | EP | disclosed |
| US-6103908-A | HYDROFORMYLATION CATALYSTS; SIMPLIFICATION, EFFICIENCY | CELANESE GMBH (DE) | 2000-08-15 | — | — | US | disclosed |