Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPLP1 | P05386 | 3/20 | 0.33 |
| ▸ | RPLP0 | P05388 | 3/20 | 0.33 |
| ▸ | RPS17 | P08708 | 3/20 | 0.33 |
| ▸ | RPSA | P08865 | 3/20 | 0.33 |
| ▸ | RPS2 | P15880 | 3/20 | 0.33 |
| ▸ | RPL35A | P18077 | 3/20 | 0.33 |
| ▸ | RPL7 | P18124 | 3/20 | 0.33 |
| ▸ | RPL17 | P18621 | 3/20 | 0.33 |
| ▸ | RPS4Y1 | P22090 | 3/20 | 0.33 |
| ▸ | RPS3 | P23396 | 3/20 | 0.33 |
| ▸ | RPS12 | P25398 | 3/20 | 0.33 |
| ▸ | RPL13 | P26373 | 3/20 | 0.33 |
| ▸ | RPL10 | P27635 | 3/20 | 0.33 |
| ▸ | RPL12 | P30050 | 3/20 | 0.33 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 3/20 | 0.33 |
| ▸ | RPL22 | P35268 | 3/20 | 0.33 |
| ▸ | RPL4 | P36578 | 3/20 | 0.33 |
| ▸ | RPS19 | P39019 | 3/20 | 0.33 |
| ▸ | RPL3 | P39023 | 3/20 | 0.33 |
| ▸ | RPL13A | P40429 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590300 | 0.85 | RPLP1 (0.37) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL4770226 | 0.83 | — | — | |
| SCHEMBL6588697 | 0.82 | — | — | |
| SCHEMBL4762987 | 0.79 | RPLP1 (0.37) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL6592789 | 0.78 | SLC6A2 (0.31) | — | |
| SCHEMBL4765366 | 0.73 | PSEN1 (0.33) | RPLP1RPLP0RPS17RPSARPS2 | |
| SCHEMBL4767101 | 0.71 | CTSD (0.37) | KCNH2 | |
| SCHEMBL6587495 | 0.71 | TRPM8 (0.35) | KCNH2 | |
| SCHEMBL6590690 | 0.71 | CXCR4 (0.32) | — | |
| SCHEMBL4763307 | 0.70 | PSEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320370-A4 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORP (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1320370-A1 | METHOD OF TREATMENT | SmithKline Beecham Corporation (US) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002017924-A1 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORPORATION (GB) | 2002-03-07 | — | — | WO | disclosed |