Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823347 | 0.95 | TRPA1 (0.54) | TRPA1EPHX1CYP1A2ALPIPKM | |
| SCHEMBL7279245 | 0.95 | TRPA1 (0.54) | TRPA1EPHX1CYP1A2ALPIPKM | |
| SCHEMBL4888635 | 0.92 | TRPA1 (0.52) | TRPA1EPHX1CYP1A2ALPIPKM | |
| SCHEMBL3418072 | 0.91 | TRPA1 (0.50) | TRPA1EPHX1CYP1A2ALPIPKM | |
| SCHEMBL108646 | 0.89 | TRPA1 (0.58) | TRPA1EPHX1CYP1A2ALPIPKM | |
| SCHEMBL537721 | 0.86 | TRPA1 (0.50) | TRPA1EPHX1CYP1A2ALPIPKM | |
| SCHEMBL105769 | 0.86 | TRPA1 (0.57) | TRPA1EPHX1CYP1A2SLC6A2TAAR1 | |
| SCHEMBL29189650 | 0.86 | TRPA1 (0.50) | TRPA1EPHX1CYP1A2ALPIPKM | |
| SCHEMBL20008956 | 0.86 | TRPA1 (0.57) | TRPA1EPHX1CYP1A2SLC6A2TAAR1 | |
| SCHEMBL30304201 | 0.84 | TDP1 (0.50) | TRPA1EPHX1CYP1A2ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6072990-A | — | — | None | — | — | JP | disclosed |
| JP-6080608-A | — | — | None | — | — | JP | disclosed |
| JP-6100486-A | — | — | None | — | — | JP | disclosed |
| JP-5320105-A | — | — | None | — | — | JP | disclosed |
| US-10961483-B2 | Method for preparing 2-monoacylglycerides | STEPAN COMPANY (US) | 2021-03-30 | — | — | US | disclosed |
| EP-3317385-B1 | METHOD FOR PREPARING 2-MONOACYLGLYCERIDES | STEPAN CO (US) | 2019-04-03 | — | — | EP | disclosed |
| US-20180187125-A1 | METHOD FOR PREPARING 2-MONOACYLGLYCERIDES | STEPAN COMPANY | 2018-07-05 | — | — | US | disclosed |
| EP-2389348-B1 | PROCESS FOR THE SYNTHESIS OF BETA GLYCEROL PHOSPHATE | SIGMA ALDRICH CO LLC (US) | 2017-11-15 | — | — | EP | disclosed |
| US-8420848-B2 | Process for the synthesis of beta glycerol phosphate | SIGMA-ALDRICH CO. LLC (US) | 2013-04-16 | — | — | US | disclosed |
| US-20120277279-A1 | Non-Steroidal Glucocorticoid Inhibitors and Their Use in Treating Inflammation, Allergy and Auto-Immune Conditions | GLAXO GROUP LIMITED | 2012-11-01 | — | — | US | disclosed |
| EP-0189305-B1 | PEPTIDE DERIVATIVES | ICI AMERICAS INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| WO-1991016315-A1 | 5-BENZYL BARBITURATE DERIVATIVES | BROWN UNIVERSITY RESEARCH FOUNDATION (US) | 1991-10-31 | — | — | WO | disclosed |
| US-5055450-A | Di-, tri- and tetrapeptides as inhibitors of human leukocyte elastase | ICI AMERICAS INC. (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0187297-B1 | ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0152965-B1 | PROCESS FOR PREPARING 2,6-SUBSTITUTED-9-(1,3-DIHYDROXY-2-PROPOXY-MENTHYL)-PURINES AND CERTAIN DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1990-10-24 | — | — | EP | disclosed |
| US-4910190-A | Containing a nitrogen containing heterocycle ring structure | ICI AMERICAS INC. (US) | 1990-03-20 | — | — | US | disclosed |
| US-4621140-A | Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxymethyl)-purines and certain derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0189305-A2 | Peptide derivatives | ICI AMERICAS INC. (US) | 1986-07-30 | — | — | EP | disclosed |
| EP-0187297-A2 | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |
| EP-0152965-A2 | Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxy-menthyl)-purines and certain derivatives | SYNTEX (U.S.A.) INC. (US) | 1985-08-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277279-A1 | Non-Steroidal Glucocorticoid Inhibitors and Their Use in Treating Inflammation, Allergy and Auto-Immune Conditions | NR3C1, SERPINA6, PTGS1 | TRPA1 2586/4885EPHX1 588/4885CYP1A2 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.