Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631342 | 0.85 | MAPT (0.54) | NPSR1PKMKMT2AMEN1NPC1 | |
| SCHEMBL9519629 | 0.85 | MAPT (0.54) | NPSR1PKMKMT2AMEN1NPC1 | |
| SCHEMBL6591901 | 0.82 | ALDH1A1 (0.52) | PKMKMT2AMEN1HPGDGAA | |
| SCHEMBL8168563 | 0.75 | MAPT (0.53) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL29860111 | 0.75 | MAPT (0.53) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL29072400 | 0.74 | MAPT (0.56) | NPSR1PKMKMT2AMEN1NPC1 | |
| SCHEMBL30570435 | 0.74 | MAPT (0.56) | NPSR1PKMKMT2AMEN1NPC1 | |
| SCHEMBL30570427 | 0.74 | MAPT (0.56) | NPSR1PKMKMT2AMEN1NPC1 | |
| SCHEMBL2886492 | 0.73 | HSD17B10 (0.55) | NPSR1PKMKMT2AMEN1NPC1 | |
| SCHEMBL2886489 | 0.73 | HSD17B10 (0.55) | NPSR1PKMKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613322-A4 | AMINOQUINOLINE COMPOUNDS | TAIGEN BIOTECHNOLOGY CO LTD (TW) | 2008-08-13 | — | — | EP | disclosed |
| US-7183413-B2 | Aminoquinoline compounds | TAIGEN BIOTECHNOLOGY (TW) | 2007-02-27 | — | — | US | disclosed |
| EP-1613322-A2 | AMINOQUINOLINE COMPOUNDS | Taigen Biotechnology (TW) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091485-A2 | AMINOQUINOLINE COMPOUNDS | TAIGEN BIOTECHNOLOGY (TW) | 2004-10-28 | — | — | WO | disclosed |
| US-20040209902-A1 | e.g., 1,4-bis[2,6-dimethylquinolin-4ylamino]butane; used to treat inflammatory and immune diseases by binding to CXCR3 receptors. | TAIGEN BIOTECHNOLOGY (TW) | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209902-A1 | e.g., 1,4-bis[2,6-dimethylquinolin-4ylamino]butane; used to treat inflammatory and immune diseases by binding to CXCR3 receptors. | CXCR3, CXCL10, CXCR1 | NPSR1 566/4885PKM 4111/4885KMT2A 1681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.