Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13989027 | 0.80 | TRPM8 (0.54) | L3MBTL1GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL6935299 | 0.76 | KMT2A (0.69) | L3MBTL1GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL29769835 | 0.75 | L3MBTL1 (0.63) | L3MBTL1GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL1084996 | 0.75 | L3MBTL1 (0.63) | L3MBTL1GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL6858019 | 0.75 | GAA (0.66) | L3MBTL1GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL4766358 | 0.73 | GAA (0.69) | L3MBTL1GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL30107521 | 0.73 | GAA (0.64) | L3MBTL1GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL6222692 | 0.73 | GAA (0.64) | L3MBTL1GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL21874386 | 0.72 | CTSC (0.52) | L3MBTL1GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL21399658 | 0.72 | GAA (0.46) | L3MBTL1GAAALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924561-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | Eli Lilly & Company (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007028083-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |