Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4774158 | 0.93 | TMPRSS2 (0.55) | TMPRSS2GAANPC1RAB9ATP53 | |
| SCHEMBL4766059 | 0.85 | KDM4E (0.50) | TMPRSS2GAANPC1RAB9AMAPT | |
| SCHEMBL4770555 | 0.85 | NPC1 (0.51) | GAANPC1RAB9ATP53MAPT | |
| Hydrochloric Acid SCHEMBL4774323 | 0.85 | KDM4E (0.49) | TMPRSS2GAANPC1RAB9AMAPT | |
| SCHEMBL4767370 | 0.83 | MEN1 (0.58) | GAANPC1RAB9ATP53MAPT | |
| SCHEMBL4772757 | 0.82 | HRH3 (0.52) | NPC1RAB9ATP53MAPTNFKB1 | |
| SCHEMBL4768475 | 0.82 | MEN1 (0.49) | TMPRSS2GAANPC1RAB9ATP53 | |
| SCHEMBL4772451 | 0.82 | TP53 (0.53) | NPC1RAB9ATP53MAPTNFKB1 | |
| SCHEMBL4768212 | 0.82 | NPC1 (0.58) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL4774628 | 0.82 | TMPRSS2 (0.61) | TMPRSS2GAANPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |