⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395636 | 0.79 | SLC6A19 (0.44) | — | |
| SCHEMBL1395660 | 0.79 | SLC6A19 (0.44) | — | |
| SCHEMBL2535335 | 0.79 | SLC6A19 (0.44) | — | |
| SCHEMBL535450 | 0.78 | — | — | |
| SCHEMBL412525 | 0.77 | — | — | |
| SCHEMBL4890524 | 0.77 | — | — | |
| SCHEMBL1515357 | 0.76 | MMP1 (0.36) | — | |
| SCHEMBL17047583 | 0.74 | TSHR (0.62) | — | |
| SCHEMBL498719 | 0.74 | — | — | |
| SCHEMBL15005 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019489-A1 | PROTEIN TYROSINE KINASE MODULATORS AND METHODS OF USE | Betta Pharmaceuticals Co., Ltd. (CN) | 2016-05-18 | — | — | EP | claimed |
| WO-2015003658-A1 | PROTEIN TYROSINE KINASE MODULATORS AND METHODS OF USE | BETTA PHARMACEUTICALS CO., LTD (CN) | 2015-01-15 | — | — | WO | claimed |
| WO-2022250069-A1 | SULFUR-CONTAINING PYRAZOLE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT INCLUDING SULFUR-CONTAINING PYRAZOLE COMPOUND AS ACTIVE INGREDIENT | 三井化学アグロ株式会社 | 2022-12-01 | — | — | WO | disclosed |
| US-20170266161-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MAKING THE SAME | SIGNUM BIOSCIENCES, INC. (US) | 2017-09-21 | — | — | US | disclosed |
| US-9486441-B2 | Compounds, compositions and methods for making the same | SIGNUM BIOSCIENCES, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-7355074-B2 | Compounds having aromatic rings and side-chain amide-functionality and a method for transporting monovalent anions across biological membranes using the same | THE UNIVERSITY OF MARYLAND (US) | 2008-04-08 | — | — | US | disclosed |
| EP-1560582-A4 | AZAINDOLE DERIVATIVES AS INHIBITORS OF p38 KINASE | SCIOS INC (US) | 2008-03-12 | — | — | EP | disclosed |
| EP-1560582-A2 | AZAINDOLE DERIVATIVES AS INHIBITORS OF p38 KINASE | SCIOS INC. (US) | 2005-08-10 | — | — | EP | disclosed |
| US-20050009921-A1 | Compounds having aromatic rings and side-chain amide-functionality and a method for transporting monovalent anions across biological membranes using the same | MARYLAND, UNIVERSITY OF | 2005-01-13 | — | — | US | disclosed |
| WO-2004032874-A2 | AZAINDOLE DERIVATIVES AS INHIBITORS OF p38 KINASE | SCIOS INC. (US) | 2004-04-22 | — | — | WO | disclosed |
| US-4067724-A | N-(1,2,4-Triazin-5-on-4-yl)-glycines and herbicidal compositions | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |