⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043620 | 0.81 | — | — | |
| SCHEMBL4896635 | 0.81 | — | — | |
| SCHEMBL6864354 | 0.79 | — | — | |
| SCHEMBL497631 | 0.79 | — | — | |
| SCHEMBL1416228 | 0.77 | — | — | |
| SCHEMBL2535335 | 0.77 | SLC6A19 (0.44) | — | |
| SCHEMBL1395660 | 0.77 | SLC6A19 (0.44) | — | |
| SCHEMBL1395636 | 0.77 | SLC6A19 (0.44) | — | |
| SCHEMBL497464 | 0.75 | FAAH (0.43) | — | |
| SCHEMBL6864828 | 0.75 | ZDHHC20 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772502-B2 | Alkylsulfinyl-substituted thiazolide compounds | ROMARK LABORATORIES, L.C. (US) | 2014-07-08 | — | — | US | claimed |
| EP-2635124-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | Romark Laboratories, L.C. (US) | 2013-09-11 | — | — | EP | claimed |
| WO-2012061190-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES L.C. (US) | 2012-05-10 | — | — | WO | claimed |
| WO-2012058378-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF SALICYLANILIDES FOR TREATMENT OF HEPATITIS VIRUSES | ROMARK LABORATORIES L.C. (US) | 2012-05-03 | — | — | WO | claimed |
| US-20120108591-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES, L.C. | 2012-05-03 | — | — | US | claimed |
| US-20120108592-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF SALICYLANILIDES FOR TREATMENT OF HEPATITIS VIRUSES | ROMARK LABORATORIES, L.C. | 2012-05-03 | — | — | US | claimed |
| WO-2008156816-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | claimed |
| US-8772502-B2 | Alkylsulfinyl-substituted thiazolide compounds | ROMARK LABORATORIES, L.C. (US) | 2014-07-08 | — | — | US | disclosed |
| EP-2635124-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | Romark Laboratories, L.C. (US) | 2013-09-11 | — | — | EP | disclosed |
| EP-2157084-B1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVE | KOWA CO (JP) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012061190-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES L.C. (US) | 2012-05-10 | — | — | WO | disclosed |
| US-20120108591-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES, L.C. | 2012-05-03 | — | — | US | disclosed |
| US-20120108592-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF SALICYLANILIDES FOR TREATMENT OF HEPATITIS VIRUSES | ROMARK LABORATORIES, L.C. | 2012-05-03 | — | — | US | disclosed |
| EP-0280951-A1 | Amino-propanol derivatives, process for their preparation and medicines containing these compounds, as well as intermediates | Roche Diagnostics GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |
| EP-0248390-A2 | Silver halide photographic light-sensitive material excellent in the super-rapid processability | KONICA CORPORATION (JP) | 1987-12-09 | — | — | EP | disclosed |
| US-4670377-A | VINYLSULFONE HARDENER, SENSITIZING DYES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1987-06-02 | — | — | US | disclosed |
| EP-0200915-A1 | Aminopropanol derivatives, process for their preparation, their use and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |
| US-4581329-A | ANTIFOGGING AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1986-04-08 | — | — | US | disclosed |
| US-4152163-A | Silver halide photographic emulsion containing cyanine and hemicyanine sensitizing dyes | FUJI PHOTO FILM CO., LTD. (JP) | 1979-05-01 | — | — | US | disclosed |
| US-4147553-A | CYANINE DYES | FUJI PHOTO FILM CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |