Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | DNTT | P04053 | 1/20 | 0.30 |
| ▸ | POLA1 | P09884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10949169 | 0.67 | DNTT (0.33) | POLBDNTTPOLA1 | |
| SCHEMBL6873744 | 0.61 | SMN1; SMN2 (0.33) | ALDH1A1 | |
| SCHEMBL7929530 | 0.59 | DNTT (0.37) | ALDH1A1POLBDNTTPOLA1 | |
| SCHEMBL17322451 | 0.58 | ALDH1A1 (0.40) | ALDH1A1POLBDNTTPOLA1 | |
| SCHEMBL23364360 | 0.56 | SETD7 (0.36) | ALDH1A1POLBDNTT | |
| SCHEMBL72876 | 0.56 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL10682082 | 0.56 | ALDH1A1 (0.35) | ALDH1A1DNTT | |
| SCHEMBL1820973 | 0.56 | DNTT (0.34) | ALDH1A1POLBDNTTPOLA1 | |
| SCHEMBL31534656 | 0.55 | DNTT (0.51) | ALDH1A1POLBDNTTPOLA1 | |
| SCHEMBL3058806 | 0.55 | DNTT (0.40) | ALDH1A1POLBDNTTPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309565-B1 | HETEROCYCLIC MUTILIN ESTERS AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2008-04-09 | — | — | EP | disclosed |
| EP-1309565-A1 | HETEROCYCLIC MUTILIN ESTERS AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012199-A1 | HETEROCYCLIC MUTILIN ESTERS AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-14 | — | — | WO | disclosed |