Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 5/20 | 0.43 |
| ▸ | TXN | P10599 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769195 | 1.00 | SCN10A (0.50) | SCN10AALDH1A1RIPK1PARP1TXN | |
| Hydrochloric Acid SCHEMBL30864304 | 0.99 | SCN10A (0.49) | SCN10AALDH1A1RIPK1PARP1TXN | |
| Hydrochloric Acid SCHEMBL30204304 | 0.99 | SCN10A (0.49) | SCN10AALDH1A1RIPK1PARP1TXN | |
| SCHEMBL23010726 | 0.83 | RAB9A (0.53) | ALDH1A1RIPK1TXNMAPTMEN1 | |
| SCHEMBL3576328 | 0.83 | ALDH1A1 (0.52) | ALDH1A1RIPK1TXNMAPTMEN1 | |
| SCHEMBL14447532 | 0.82 | RAB9A (0.55) | ALDH1A1RIPK1TXNMAPTMEN1 | |
| SCHEMBL7970193 | 0.81 | ALDH1A1 (0.48) | ALDH1A1RIPK1PARP1TXNMAPT | |
| SCHEMBL12509313 | 0.80 | SCN10A (0.58) | SCN10APARP1 | |
| SCHEMBL1645792 | 0.79 | SCN10A (0.56) | SCN10APARP1 | |
| SCHEMBL9605019 | 0.79 | SCN10A (0.56) | SCN10APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973898-A1 | PDF INHIBITORS | Novartis AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007077186-A1 | PDF INHIBITORS | NOVARTIS AG (CH) | 2007-07-12 | — | — | WO | disclosed |