SCHEMBL2340182

SCHEMBL2340182

CCCCONOCCCC

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.45
ADRB1 P08588 1/20 0.45
ADRB3 P13945 1/20 0.45
TSHR P16473 7/20 0.39
CYP3A4 P08684 2/20 0.39
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
THRB P10828 1/20 0.35
ATM Q13315 1/20 0.35
HPGD P15428 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27858041 0.91 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL8044051 0.90 THRB (0.41) TSHRALDH1A1CA1CA2THRB
SCHEMBL8006623 0.88 THRB (0.47) TSHRCA1CA2THRB
SCHEMBL295951 0.88 THRB (0.47) TSHRCA1CA2THRB
SCHEMBL4638313 0.88 THRB (0.47) TSHRCA1CA2THRB
SCHEMBL6264096 0.88 THRB (0.47) TSHRCA1CA2THRB
SCHEMBL185163 0.88 THRB (0.47) TSHRCA1CA2THRB
SCHEMBL16053329 0.88 THRB (0.47) TSHRCA1CA2THRB
SCHEMBL14391184 0.85
SCHEMBL8466156 0.81 ADRB2 (0.36) ADRB2ADRB1ADRB3TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118159632-A Perfume and perfume mixture 西姆莱斯股份公司 2024-06-07 CN disclosed
CN-113710331-B Antimicrobial mixture 西姆莱斯股份公司 2024-03-22 CN disclosed
CN-116963710-A Medicine for preventing and treating hyperpigmentation 西姆莱斯股份公司 2023-10-27 CN disclosed
CN-116806825-A Antimicrobial mixture 西姆莱斯股份公司 2023-09-29 CN disclosed
CN-115536846-B Preparation method of amino silicone oil modified hyaluronic acid for cosmetics, amino silicone oil modified hyaluronic acid and application 上海臻臣化妆品有限公司 2023-08-11 CN disclosed
CN-116583261-A Method for combating microorganisms using menthol derivatives 西姆莱斯股份公司 2023-08-11 CN disclosed
CN-116490160-A A mixture containing 1, 2-alkanediol 西姆莱斯股份公司 2023-07-25 CN disclosed
CN-113543637-B Antimicrobial mixture 西姆莱斯股份公司 2023-07-14 CN disclosed
CN-115894139-A High-solid-content high-combustion-rate butylated hydroxytoluene composite solid propellant and preparation method thereof 湖北三江航天江河化工科技有限公司 2023-04-04 CN disclosed
EP-1201644-B1 A process for the prepraration of a dihydroxyamino compound DAICEL CHEM (JP) 2011-08-24 EP disclosed
EP-1201644-A2 A process for the prepration of a dihydroxyamino compound Daicel Chemical Industries, Ltd. (JP) 2002-05-02 EP disclosed
US-5874624-A REACTING EPOXY COMPOUND AND AN AMINO COMPOUND AT A SPECIFIED TEMPERATURE AND PRESSURE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-02-23 US disclosed
EP-0839802-A2 A process for the preparation of a dihydroxyamino compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-05-06 EP disclosed
US-4134842-A Molded plastic bearing assembly KAMATICS CORPORATION (US) 1979-01-16 US disclosed
US-4048370-A Shaped bearing member KAMATICS CORPORATION (US) 1977-09-13 US disclosed