Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4662970 | 1.00 | S1PR5 (0.53) | S1PR5ALDH1A1PDCD1LG2CD274S1PR4 | |
| SCHEMBL4664465 | 0.82 | TSHR (0.60) | S1PR5ALDH1A1PDCD1LG2CD274 | |
| SCHEMBL5110651 | 0.82 | TSHR (0.60) | S1PR5ALDH1A1PDCD1LG2CD274 | |
| SCHEMBL4662842 | 0.80 | S1PR5 (0.57) | S1PR5ALDH1A1PDCD1LG2CD274S1PR4 | |
| SCHEMBL4664522 | 0.79 | FAAH (0.55) | S1PR5ALDH1A1PDCD1LG2CD274S1PR4 | |
| SCHEMBL4664521 | 0.79 | FAAH (0.55) | S1PR5ALDH1A1PDCD1LG2CD274S1PR4 | |
| SCHEMBL2160181 | 0.77 | ALDH1A1 (0.61) | S1PR5ALDH1A1PDCD1LG2CD274S1PR4 | |
| SCHEMBL16301219 | 0.76 | S1PR5 (0.77) | S1PR5ALDH1A1S1PR4S1PR1S1PR3 | |
| SCHEMBL9037650 | 0.76 | S1PR5 (0.77) | S1PR5ALDH1A1S1PR4S1PR1S1PR3 | |
| SCHEMBL250506 | 0.76 | S1PR5 (0.77) | S1PR5ALDH1A1S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007787-A2 | HCV INHIBITORS COMPRISING BETA AMINO ACIDS AND THEIR USES | Novartis AG (CH) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007121124-A2 | HCV INHIBITORS COMPRISING BETA AMINO ACIDS AND THEIR USES | NOVARTIS AG (CH) | 2007-10-25 | — | — | WO | disclosed |