Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.54 |
| ▸ | MPO | P05164 | 5/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19463742 | 0.83 | TDP1 (0.44) | MTNR1ALMNAMEN1KMT2A | |
| SCHEMBL961507 | 0.81 | MTNR1A (0.63) | MTNR1AMPOKDM4EMEN1KMT2A | |
| SCHEMBL5159102 | 0.79 | MEN1 (0.60) | MTNR1ATLR8PARP1MEN1KMT2A | |
| SCHEMBL3886508 | 0.74 | GABRA1 (0.41) | LMNAKDM4EMEN1KMT2A | |
| SCHEMBL6871577 | 0.74 | PNMT (0.39) | MTNR1A | |
| SCHEMBL9321175 | 0.73 | MTNR1A (0.47) | MTNR1AMPOCAPN1EGFRSRC | |
| SCHEMBL27448488 | 0.72 | MEN1 (0.35) | MTNR1AMPOMEN1KMT2AGPR84 | |
| SCHEMBL1284856 | 0.72 | MTNR1A (0.62) | MTNR1AMPOTLR8MEN1KMT2A | |
| SCHEMBL7316097 | 0.72 | PARP1 (0.50) | MTNR1AMPOCAPN1PARP1EGFR | |
| SCHEMBL7536240 | 0.71 | TLR8 (0.43) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411506-A1 | TUMOR SUPPRESSION USING HUMAN PLACENTA-DERIVED INTERMEDIATE NATURAL KILLER CELLS AND IMMUNOMODULATORY COMPOUNDS | Anthrogenesis Corporation (US) | 2012-02-01 | — | — | EP | disclosed |