Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999001 | 0.81 | NQO2 (0.62) | NQO2NPSR1MTNR1AMEN1MAPT | |
| SCHEMBL3886508 | 0.77 | GABRA1 (0.41) | MEN1MAPTKMT2A | |
| SCHEMBL14204990 | 0.74 | SETDB1 (0.59) | NQO2NPSR1MTNR1AMTNR1BKMT2A | |
| SCHEMBL27931462 | 0.74 | ALDH1A1 (0.55) | NQO2NPSR1MTNR1AMTNR1BMEN1 | |
| SCHEMBL10383768 | 0.74 | NQO2 (0.54) | NQO2NPSR1MTNR1AMTNR1BMEN1 | |
| SCHEMBL19463742 | 0.71 | TDP1 (0.44) | NPSR1MTNR1AMEN1MAPTKMT2A | |
| SCHEMBL16136256 | 0.70 | NPSR1 (0.47) | NQO2NPSR1MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL14651452 | 0.70 | SETDB1 (0.54) | NQO2NPSR1MTNR1AMTNR1BKMT2A | |
| SCHEMBL24499204 | 0.69 | RIPK1 (0.36) | — | |
| SCHEMBL18255173 | 0.69 | IAPP (0.56) | NQO2NPSR1MTNR1AMTNR1BSETDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411506-A1 | TUMOR SUPPRESSION USING HUMAN PLACENTA-DERIVED INTERMEDIATE NATURAL KILLER CELLS AND IMMUNOMODULATORY COMPOUNDS | Anthrogenesis Corporation (US) | 2012-02-01 | — | — | EP | disclosed |