Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.58 |
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769744 | 0.93 | KMT2A (0.57) | ACHEESR1LMNACYP1A2CYP2D6 | |
| SCHEMBL8621504 | 0.91 | ACHE (0.59) | ACHEESR1LMNAADRA2AADORA3 | |
| SCHEMBL7200875 | 0.91 | ACHE (0.59) | ACHEESR1LMNAADRA2AADORA3 | |
| SCHEMBL8624782 | 0.87 | ACHE (0.57) | ACHEESR1LMNAADRA2AADORA3 | |
| SCHEMBL7201386 | 0.87 | CNR2 (0.58) | ACHEESR1LMNAADRA2AADORA3 | |
| SCHEMBL8844859 | 0.84 | ESR1 (0.45) | ACHEESR1LMNACYP1A2CYP2D6 | |
| SCHEMBL8590341 | 0.84 | CYP1A2 (0.55) | ACHEESR1LMNACYP1A2CYP2D6 | |
| SCHEMBL5322076 | 0.82 | CHRNB2 (0.58) | ACHESMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21382248 | 0.81 | KMT2A (0.57) | ACHE | |
| SCHEMBL8758551 | 0.81 | ACHE (0.49) | ACHEALDH1A1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |