SCHEMBL4770264

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22829251	0.88	TDP1 (0.52)	TDP1SIGMAR1MEN1KMT2ANAMPT
	SCHEMBL22829250	0.88	TDP1 (0.52)	TDP1SIGMAR1MEN1KMT2ANAMPT
	SCHEMBL2811392	0.82	PDK4 (0.60)	MEN1KMT2ANAMPTALDH1A1NPC1
	SCHEMBL4779256	0.79	MAPT (0.45)	TDP1SIGMAR1MEN1KMT2ANAMPT
	SCHEMBL19784609	0.77	SIGMAR1 (0.43)	TDP1SIGMAR1CNR1
	SCHEMBL12801757	0.77	LNPEP (0.48)	TDP1SIGMAR1MEN1KMT2ANAMPT
	SCHEMBL19782549	0.77	CHRM3 (0.55)	TDP1SIGMAR1
	SCHEMBL4775621	0.77	MEN1 (0.61)	TDP1MEN1KMT2AALDH1A1NPC1
	SCHEMBL4793472	0.76	CCR1 (0.47)	KMT2ANPC1CNR1
	SCHEMBL19989639	0.75	NAMPT (0.67)	MEN1KMT2ANAMPTALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.