Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769973 | 0.94 | HTR2B (0.52) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL4774934 | 0.89 | MEN1 (0.45) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL946709 | 0.88 | NR3C1 (0.47) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL949737 | 0.87 | HTR2A (0.49) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL946625 | 0.86 | HTR2A (0.45) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL4778974 | 0.86 | CTSV (0.46) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL948641 | 0.84 | HTR2A (0.51) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL946598 | 0.82 | MGAM (0.46) | HTR2ANR4A2GUSBGAASRC | |
| SCHEMBL950480 | 0.79 | HTR2A (0.55) | HTR2AHTR2CHTR2BMTNR1AMTNR1B | |
| SCHEMBL947466 | 0.77 | GUSB (0.46) | HTR2AHTR2CHTR2BMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581492-B1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2008-07-16 | — | — | EP | disclosed |