Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769973 | 0.92 | HTR2B (0.52) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL4770631 | 0.89 | HTR2A (0.46) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL946709 | 0.86 | NR3C1 (0.47) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL949737 | 0.85 | HTR2A (0.49) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL950364 | 0.84 | MEN1 (0.56) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL4778974 | 0.84 | CTSV (0.46) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL948077 | 0.83 | MGAM (0.45) | NR4A2MGAMGAASIMGAM2 | |
| SCHEMBL948641 | 0.78 | HTR2A (0.51) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL950480 | 0.77 | HTR2A (0.55) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL950579 | 0.76 | GUSB (0.47) | MEN1KMT2ANR4A2MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581492-B1 | N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2008-07-16 | — | — | EP | disclosed |