Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4767843 | 0.95 | MAPT (0.46) | MAPTALDH1A1HRH3BLMRAB9A | |
| SCHEMBL4765178 | 0.89 | ALDH1A1 (0.58) | MAPTALDH1A1HRH3GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL4765416 | 0.88 | ALDH1A1 (0.57) | MAPTALDH1A1GAAMAPK1 | |
| SCHEMBL4765384 | 0.87 | MAPT (0.50) | MAPTALDH1A1HRH3BLMGAA | |
| Trifluoroacetic Acid SCHEMBL4765164 | 0.82 | MAPT (0.49) | MAPTALDH1A1HRH3GAAMAPK1 | |
| SCHEMBL4768367 | 0.79 | NPC1 (0.48) | ALDH1A1HRH3RAB9ANPC1HPGD | |
| Hydrochloric Acid SCHEMBL4770710 | 0.78 | NPC1 (0.47) | HRH3RAB9ANPC1HPGD | |
| SCHEMBL4774462 | 0.77 | RAB9A (0.59) | RAB9ANPC1HPGD | |
| SCHEMBL4765305 | 0.76 | RAB9A (0.48) | HRH3RAB9ANPC1HPGD | |
| Hydrochloric Acid SCHEMBL4774495 | 0.75 | RAB9A (0.47) | HRH3RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |