SCHEMBL4770817

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4770508	0.89	RXFP1 (0.40)	HTR1ARXFP1SYKMCHR1PDE3B
	SCHEMBL4773849	0.85	METAP1 (0.41)	HTR1AHTR2CRXFP1TSHRKDM4E
	SCHEMBL6288623	0.83	HRH3 (0.41)	HRH3CYP4F2CYP4A11KDM4EMCHR1
	SCHEMBL4765464	0.83	SYK (0.39)	HTR2CRXFP1SYKPDE3BPDE3A
	SCHEMBL4766183	0.83	RXFP1 (0.41)	RXFP1SYKTSHRKDM4EHTT
	SCHEMBL4770809	0.83	KDM4E (0.38)	HTR1AHTR2CRXFP1SYKTSHR
	Hydrochloric Acid SCHEMBL4769740	0.82	SYK (0.39)	HTR2CRXFP1SYKPDE3BPDE3A
	SCHEMBL4771981	0.81	RXFP1 (0.38)	HRH3RXFP1SYKPDE3BPDE3A
	SCHEMBL4774234	0.81	SYK (0.38)	HRH3RXFP1SYKPDE3BPDE3A
	SCHEMBL4769430	0.81	RXFP1 (0.37)	HRH3HTR1AHTR2CRXFP1SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.