SCHEMBL4770940

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4779064	0.84	TSHR (0.51)	KDM4ETSHRDPP4DPP8FAP
	SCHEMBL4770627	0.80	DPP4 (0.53)	KDM4ETSHRCYP3A4DPP4DPP8
	SCHEMBL4779980	0.78	ALDH1A1 (0.62)	KDM4ETSHRCYP3A4DPP4DPP8
	SCHEMBL4776766	0.78	L3MBTL1 (0.53)	KDM4EDPP4DPP8FAPDPP9
	SCHEMBL14456799	0.77	KDM4E (0.56)	KDM4ETSHRCYP3A4ALDH1A1ATM
	SCHEMBL4776506	0.77	KDM4E (0.57)	KDM4ETSHRDPP4ALDH1A1TDP1
	SCHEMBL4779266	0.77	HDAC8 (0.57)	KDM4ETSHR
	SCHEMBL4775817	0.76	CACNA2D1 (0.54)	DPP4DPP8FAPDPP9MEN1
	SCHEMBL4908880	0.76	EPHX2 (0.47)	KDM4ETSHRCYP3A4DPP8ALDH1A1
	SCHEMBL4775039	0.75	HDAC8 (0.59)	KDM4ETSHRALDH1A1ATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.