Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.66 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28109821 | 0.86 | SMN1; SMN2 (0.59) | KEAP1NFE2L2KDM4EALDH1A1LMNA | |
| SCHEMBL2334379 | 0.85 | KEAP1 (0.56) | KEAP1NFE2L2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL6501947 | 0.84 | KMT2A (0.63) | KEAP1NFE2L2KDM4EALDH1A1LMNA | |
| SCHEMBL11579297 | 0.84 | POLB (0.64) | KEAP1NFE2L2KDM4EALDH1A1KMT2A | |
| SCHEMBL13724595 | 0.84 | KDM4E (0.55) | KEAP1NFE2L2KDM4EALDH1A1KMT2A | |
| SCHEMBL7961836 | 0.84 | KEAP1 (0.68) | KEAP1NFE2L2MAPK1PPARG | |
| SCHEMBL10693747 | 0.83 | MAPT (0.55) | KEAP1NFE2L2KDM4ELMNAHSD17B10 | |
| SCHEMBL15705773 | 0.83 | MMP1 (0.54) | KDM4EALDH1A1KMT2AGAA | |
| SCHEMBL30721053 | 0.83 | KEAP1 (0.54) | KEAP1NFE2L2KDM4ELMNAHSD17B10 | |
| SCHEMBL11603483 | 0.82 | RECQL (0.59) | KEAP1NFE2L2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118777455-A | Method for detecting content of glycine methyl ester and glycine in p-toluenesulfonic acid by high performance liquid chromatography | 湖北泰盛化工有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-113717102-B | New preparation method of isoquinoline compound | 南通常佑药业科技有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-117825530-A | Method for detecting methyl tosylglycine | 中山奕安泰医药科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| EP-0384341-A2 | New proline derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1990-08-29 | — | — | EP | claimed |
| CN-115838354-B | Thyroid hormone receptor beta agonist compound and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2025-05-13 | — | — | CN | disclosed |
| CN-119039221-A | Synthesis method of roflumilast | 沈阳药科大学 | 2024-11-29 | — | — | CN | disclosed |
| CN-118777455-A | Method for detecting content of glycine methyl ester and glycine in p-toluenesulfonic acid by high performance liquid chromatography | 湖北泰盛化工有限公司 | 2024-10-15 | — | — | CN | disclosed |
| WO-2024153155-A1 | DOUBLE-HETEROCYCLIC WRN INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 成都微芯药业有限公司 | 2024-07-25 | — | — | WO | disclosed |
| CN-117825530-A | Method for detecting methyl tosylglycine | 中山奕安泰医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117825530-A | Method for detecting methyl tosylglycine | 中山奕安泰医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117825530-A | Method for detecting methyl tosylglycine | 中山奕安泰医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-116891448-A | Preparation method of roflumilast intermediate III | 上海医药集团青岛国风药业股份有限公司 | 2023-10-17 | — | — | CN | disclosed |
| EP-1001971-A1 | DIPEPTIDE AND RELATED COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-24 | — | — | EP | disclosed |
| EP-1001973-A1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006433-A1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | disclosed |
| WO-1999006432-A1 | DIPEPTIDE AND RELATED COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | disclosed |
| EP-0553962-A1 | Corrosion inhibiting compositions | CIBA-GEIGY AG (CH) | 1993-08-04 | — | — | EP | disclosed |
| US-5158970-A | Prolylendopeplidase inhibitors; antiamnesia | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0384341-A2 | New proline derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4344862-A | Reaction products of sulfonamido-carboxylic acids or carboxamido-carboxylic acids with alkanolamines, and their use as low-foaming corrosion inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |