Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.52 |
| ▸ | AGER | Q15109 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200356 | 0.85 | KMT2A (0.55) | MAPTMCOLN3LMNAKDM4EHSD17B10 | |
| SCHEMBL4771204 | 0.83 | KEAP1 (0.66) | LMNAKDM4EHSD17B10KEAP1NFE2L2 | |
| SCHEMBL28109821 | 0.83 | SMN1; SMN2 (0.59) | MAPTMCOLN3LMNAKDM4EHSD17B10 | |
| SCHEMBL5722107 | 0.82 | CCR5 (0.53) | LMNASMN1; SMN2MAPK1KMT2APOLB | |
| SCHEMBL10692733 | 0.82 | GLA (0.59) | MAPTMCOLN3LMNAKDM4EHSD17B10 | |
| SCHEMBL13434084 | 0.82 | MAPT (0.57) | MAPTMCOLN3LMNAKDM4EHSD17B10 | |
| SCHEMBL4332702 | 0.80 | MAPT (0.55) | MAPTMCOLN3LMNAKDM4EHSD17B10 | |
| SCHEMBL3178219 | 0.80 | MAPT (0.55) | MAPTMCOLN3LMNAKDM4EHSD17B10 | |
| SCHEMBL3274174 | 0.80 | MAPT (0.55) | MAPTMCOLN3LMNAKDM4EHSD17B10 | |
| SCHEMBL14873525 | 0.79 | MAPT (0.50) | MAPTMCOLN3LMNAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764570-A | MODIFYING MELAMINE-FORMALDEHYDE RESINS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1988-08-16 | — | — | US | disclosed |