Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848261 | 0.88 | KMT2A (0.43) | ALDH1A1SMN1; SMN2KDM4EACE | |
| SCHEMBL2032193 | 0.84 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4EITGB3ITGB1 | |
| SCHEMBL1818486 | 0.84 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4EITGB3ITGB1 | |
| SCHEMBL7959886 | 0.81 | KDM4E (0.47) | ALDH1A1SMN1; SMN2KDM4EITGB3ITGB1 | |
| SCHEMBL7973454 | 0.81 | KDM4E (0.47) | ALDH1A1SMN1; SMN2KDM4EITGB3ITGB1 | |
| SCHEMBL7973302 | 0.81 | KDM4E (0.47) | ALDH1A1SMN1; SMN2KDM4EITGB3ITGB1 | |
| SCHEMBL7976128 | 0.81 | KDM4E (0.47) | ALDH1A1SMN1; SMN2KDM4EITGB3ITGB1 | |
| SCHEMBL28860925 | 0.81 | KDM4E (0.47) | ALDH1A1SMN1; SMN2KDM4EITGB3ITGB1 | |
| SCHEMBL7973306 | 0.81 | KDM4E (0.47) | ALDH1A1SMN1; SMN2KDM4EITGB3ITGB1 | |
| SCHEMBL7959881 | 0.81 | KDM4E (0.47) | ALDH1A1SMN1; SMN2KDM4EITGB3ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957058-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007064749-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |