Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | NNMT | P40261 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | STAMBP | O95630 | 1/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3121440 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1ALOX15HSD17B10NNMT | |
| SCHEMBL185994 | 0.80 | ALDH1A1 (1.00) | KDM4EALDH1A1ALOX15HSD17B10HPGD | |
| SCHEMBL23407776 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1ALOX15HSD17B10HPGD | |
| SCHEMBL3132631 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1ALOX15HSD17B10NNMT | |
| SCHEMBL4304705 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1ALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL29337499 | 0.78 | ALDH1A1 (0.55) | KDM4EALDH1A1ALOX15HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL22042710 | 0.77 | ALDH1A1 (0.53) | KDM4EALDH1A1ALOX15HSD17B10HPGD | |
| SCHEMBL669121 | 0.77 | NNMT (0.52) | KDM4EHSD17B10NNMTSMN1; SMN2POLB | |
| SCHEMBL3407188 | 0.76 | NNMT (0.56) | KDM4EHSD17B10NNMTSMN1; SMN2POLB | |
| SCHEMBL4315212 | 0.75 | ALDH1A1 (0.52) | KDM4EALDH1A1ALOX15HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4405344-A2 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | Xenon Pharmaceuticals Inc. (CA) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023049369-A2 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | XENON PHARMACEUTICALS INC. (CA) | 2023-03-30 | — | — | WO | disclosed |
| EP-1937682-A1 | MET KINASE INHIBITORS | Brystol-Myers Squibb Company (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007041379-A1 | MET KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-12 | — | — | WO | disclosed |