Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4775421 | 0.96 | KCNK3 (0.51) | MAPK14PTGS1LMNAMAPTKCNK3 | |
| SCHEMBL4768203 | 0.89 | TRPV4 (0.59) | PTGS1MAPTHTTRAB9AKMT2A | |
| SCHEMBL4772670 | 0.86 | NPC1 (0.71) | MAPK14LMNAMAPTKCNK3HTT | |
| Trifluoroacetic Acid SCHEMBL4774281 | 0.86 | SLC2A1 (0.58) | MAPTHTTRAB9AKMT2ANPC1 | |
| SCHEMBL4772154 | 0.84 | NPC1 (0.52) | LMNAMAPTHTTRAB9AKMT2A | |
| SCHEMBL4767344 | 0.84 | TDP1 (0.58) | MAPK14LMNAMAPTKCNK3HTT | |
| Trifluoroacetic Acid SCHEMBL4770822 | 0.82 | RAB9A (0.53) | MAPK14LMNAMAPTKCNK3RAB9A | |
| Trifluoroacetic Acid SCHEMBL4770267 | 0.82 | HRH3 (0.57) | HTTRAB9AKMT2ANPC1NFKB1 | |
| SCHEMBL4765222 | 0.82 | HRH3 (0.52) | MAPTRAB9ASMN1; SMN2TRPV4 | |
| SCHEMBL4773028 | 0.82 | RAB9A (0.60) | MAPK14LMNAMAPTKCNK3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |