Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4775692 | 0.94 | RAB9A (0.52) | RAB9AKDM4ENPC1MEN1KMT2A | |
| SCHEMBL4765391 | 0.88 | RXFP1 (0.51) | RAB9AKDM4ENPC1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4767186 | 0.83 | MAPT (0.46) | RAB9AMEN1KMT2AMAPTHPGD | |
| SCHEMBL4770201 | 0.81 | SMN1; SMN2 (0.50) | RAB9AKDM4ENPC1MEN1KMT2A | |
| SCHEMBL4772409 | 0.81 | RAB9A (0.51) | RAB9AKDM4ENPC1MEN1KMT2A | |
| SCHEMBL4765111 | 0.80 | HRH3 (0.46) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4775503 | 0.80 | MAPT (0.54) | RAB9AKDM4ENPC1MEN1KMT2A | |
| SCHEMBL4765905 | 0.80 | NPC1 (0.69) | RAB9AKDM4ENPC1MEN1KMT2A | |
| SCHEMBL4770147 | 0.79 | HRH3 (0.46) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL4765424 | 0.79 | HRH3 (0.47) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |