SCHEMBL4772682

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7829888	0.86	HTT (0.53)	KMT2AHTTCYP1A2KDM4EALDH1A1
	SCHEMBL15670580	0.85	HTT (0.51)	KMT2AHTTCYP1A2KDM4EALDH1A1
	SCHEMBL8377550	0.85	KMT2A (0.55)	KMT2AHTTCYP1A2KDM4EALDH1A1
	SCHEMBL17101127	0.81	ALDH1A1 (0.61)	KMT2AHTTKDM4EALDH1A1POLB
	SCHEMBL8314534	0.80	HTT (0.46)	KMT2AHTTCYP1A2KDM4EALDH1A1
	SCHEMBL2420773	0.74	KDM4E (0.54)	KMT2AHTTKDM4EALDH1A1POLB
	SCHEMBL18754397	0.74	HTT (0.58)	KMT2AHTTCYP1A2KDM4EALDH1A1
	SCHEMBL196599	0.72	KMT2A (1.00)	KMT2AHTTKDM4EALDH1A1POLB
	SCHEMBL8315301	0.72	KMT2A (1.00)	KMT2AHTTKDM4EALDH1A1POLB
	SCHEMBL21849002	0.71	HTT (0.51)	KMT2AHTTCYP1A2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.