SCHEMBL4772889

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4765567	0.96	PRMT5 (0.43)	NPC1RAB9ATSHRMAPK1HSD17B10
	SCHEMBL4771708	0.87	PRMT5 (0.40)	TSHRHSD17B10PRMT5SMN1; SMN2KMT2A
	SCHEMBL4774280	0.87	KMT2A (0.43)	NPC1RAB9ATSHRMAPK1HSD17B10
	Hydrochloric Acid SCHEMBL4792801	0.87	KMT2A (0.42)	NPC1RAB9ATSHRMAPK1HSD17B10
	SCHEMBL4767877	0.86	KDM4E (0.48)	NPC1RAB9ATSHRMAPK1HSD17B10
	SCHEMBL8115332	0.85	KDM1A (0.43)	TSHRSMN1; SMN2KMT2ACYP1A2CYP2C19
	Hydrochloric Acid SCHEMBL4766516	0.85	KDM4E (0.47)	TSHRMAPK1HSD17B10SMN1; SMN2KMT2A
	Hydrochloric Acid SCHEMBL4773135	0.85	KDM1A (0.42)	TSHRSMN1; SMN2KMT2ACYP1A2CYP2C19
	Hydrochloric Acid SCHEMBL4770743	0.83	PRMT5 (0.41)	NPC1RAB9AMAPK1HSD17B10PRMT5
	SCHEMBL4772877	0.83	PRMT5 (0.47)	NPC1RAB9ATSHRMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.