Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.50 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14321366 | 0.83 | KDM4C (0.47) | CSNK1A1TYRO3DYRK1BGRM5MAPT | |
| SCHEMBL251450 | 0.77 | PARP1 (0.45) | CSNK1A1TYRO3DYRK1BBCAT2GRM5 | |
| SCHEMBL31227695 | 0.77 | CSNK1A1 (0.57) | CSNK1A1TYRO3DYRK1BBCAT2NPC1 | |
| SCHEMBL997870 | 0.77 | CSNK1A1 (0.57) | CSNK1A1TYRO3DYRK1BBCAT2NPC1 | |
| SCHEMBL2653334 | 0.73 | ALDH1A1 (0.61) | CSNK1A1TYRO3DYRK1BBCAT2NPC1 | |
| SCHEMBL30675982 | 0.73 | ALDH1A1 (0.61) | CSNK1A1TYRO3DYRK1BBCAT2NPC1 | |
| SCHEMBL251448 | 0.73 | PARP1 (0.44) | CSNK1A1TYRO3DYRK1BBCAT2NPC1 | |
| SCHEMBL30514077 | 0.73 | BCAT2 (0.74) | CSNK1A1TYRO3DYRK1BBCAT2NPC1 | |
| SCHEMBL210767 | 0.73 | BCAT2 (0.74) | CSNK1A1TYRO3DYRK1BBCAT2NPC1 | |
| SCHEMBL15125436 | 0.73 | GAA (0.52) | NPC1RAB9AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058694-A | Contain 1,2, the Herbicidal combinations of 4-triazole-3-formamide and control method for weed with said composition | KUREHA CHEMICAL IND CO LTD (JP) | 1992-02-19 | — | — | CN | claimed |
| CN-86108483-A | 1. 2, 4-triazole-3-carboxamide compound, preparation method thereof and herbicidal composition containing same | — | 1987-09-16 | — | — | CN | claimed |
| EP-1322309-B1 | HIGH AFFINITY SMALL MOLECULE C5A RECEPTOR MODULATORS | NEUROGEN CORP (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7271270-B2 | High affinity small molecule C5a receptor modulators | NEUROGEN CORPORATION (US) | 2007-09-18 | — | — | US | disclosed |
| US-20070027158-A1 | High affinity small molecule C5a receptor modulators | NEUROGEN CORPORATION | 2007-02-01 | — | — | US | disclosed |
| US-6884815-B1 | High affinity small molecule C5a receptor modulators | NEUROGEN CORPORATION (US) | 2005-04-26 | — | — | US | disclosed |
| EP-1322309-A4 | HIGH AFFINITY SMALL MOLECULE C5A RECEPTOR MODULATORS | NEUROGEN CORP (US) | 2004-10-13 | — | — | EP | disclosed |
| US-6723743-B1 | TREATING PATIENT SUFFERING FROM RHEUMATOID ARTHRITIS, PSORIASIS, BRONCHIAL ASTHMA, ALZHEIMER'S DISEASE, MYOCARDIAL INFARCTION OR ATHEROSCLEROSIS | NEUROGEN CORPORATION | 2004-04-20 | — | — | US | disclosed |
| CN-1454086-A | High affinity small molecule C5A receptor modulators | NEUROGEN CORP (US) | 2003-11-05 | — | — | CN | disclosed |
| EP-1322309-A2 | HIGH AFFINITY SMALL MOLECULE C5A RECEPTOR MODULATORS | Neurogen Corporation (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002049993-A2 | HIGH AFFINITY SMALL MOLECULE C5A RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2002-06-27 | — | — | WO | disclosed |
| CN-1058694-A | Contain 1,2, the Herbicidal combinations of 4-triazole-3-formamide and control method for weed with said composition | KUREHA CHEMICAL IND CO LTD (JP) | 1992-02-19 | — | — | CN | disclosed |
| CN-1015455-B | Process for producing 1, 2, 4-triazole-3-carboxamide compound | KUREHA CHEMICAL IND CO LTD (JP) | 1992-02-12 | — | — | CN | disclosed |
| CN-86108483-A | 1. 2, 4-triazole-3-carboxamide compound, preparation method thereof and herbicidal composition containing same | — | 1987-09-16 | — | — | CN | disclosed |
| CN-86108483-A | 1. 2, 4-triazole-3-carboxamide compound, preparation method thereof and herbicidal composition containing same | — | 1987-09-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027158-A1 | High affinity small molecule C5a receptor modulators | C3AR1, C5AR1, C5AR2 | CSNK1A1 4171/4885TYRO3 222/4885DYRK1B 2632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.